Results 151 to 160 of about 1,653,806 (310)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Basic Science Building (Wittson Hall) Amphitheater
, 2015 •Basic Science building (now Wittson Hall) amphitheater •Circa 1969 •The Basic Science building amphitheater provided 294 seats. •The Basic Science building was renamed Wittson Hall in 1972, in honor of retiring UNMC Chancellor Cecil Wittson.https ...
University of Nebraska Medical Center
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Insights and Practical Considerations for Communicating Basic Science
Basic science, also known as fundamental, curiosity-driven, and discovery science, is seldom the focus of the science communication universe. The Science Public Engagement Partnership (SciPEP) between The Kavli Foundation and the U.S.
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
, 2018 Science is taught as integrated science in colleges of education, Junior High School (JHS), Upper Primary (Basic 4-6) and Natural Science in Lower Primary (Basic 1-3).
Osei-Himah, Valentina +3 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 2014 This study evaluated the topical coverage and chapter summaries of 12 (twelve) approved basic science textbooks in Ebonyi State junior secondary schools. The study was carried out in Ebonyi State of Nigeria.
Omebe, Chinyere A., Nnachi, Ndukwe Oji
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source