Results 41 to 50 of about 168,995 (306)

Degradation of Toluene and Trichloroethylene by Burkholderia cepacia G4 in Growth-Limited Fed-Batch Culture [PDF]

, 1996
Burkholderia (Pseudomonas) cepacia G4 was cultivated in a fed-batch bioreactor on either toluene or toluene plus trichloroethylene (TCE). The culture was allowed to reach a constant cell density under conditions in which the amount of toluene supplied ...
Astrid E. Mars, Janssen, D.B., Dolfing, Jan,, Dolfing, J., Jan Dolfing, Mars, Astrid E.,, Janssen, Dick B., Dick B. Janssen, Dolfing, Jan, Houwing, Joukje, Janssen, Dick B.,, Houwing, J., Houwing, Joukje,, Mars, Astrid E., Joukje Houwing, Mars, A.   +15 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Diversity of Dibenzofuran-Utilizing Bacteria Isolated by Direct-Plating and Enrichment Methods

Indonesian Journal of Biotechnology, 2012
The effect of enrichment bias on the diversity of Dibenzofuran (DBF)-degrading bacteria recovered from soil was evaluated by direct plating, plating after in-soil adaptation, and plating after batch culture enrichment.
Irfan Dwidya Prijambada, Jaka Widada, Pintaka Kusumaningtyas, Dhani Suryawan   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Pseudomonas aeruginosa PAO1 preferentially grows as aggregates in liquid batch cultures and disperses upon starvation [PDF]

, 2009
In both natural and artificial environments, bacteria predominantly grow in biofilms, and bacteria often disperse from biofilms as freely suspended single-cells.
Klebensberger Janosch, Diane McDougald, Barraud, N, Kjelleberg Staffan, Rice Scott A., Webb, Jeremy S., Rice, Scott A., Kjelleberg, Staffan, Rice, SA, Ausubel, Frederick M., Nicolas Barraud, Klebensberger, J, Schleheck, D, Klebensberger, Janosch, David Schleheck, Schleheck, David, Kjelleberg, S, McDougald Diane, Staffan Kjelleberg, Barraud Nicolas, Webb Jeremy S., Jeremy S Webb, Barraud, Nicolas, Scott A Rice, Schleheck David, McDougald, Diane, McDougald, D, Webb, JS, Janosch Klebensberger   +28 more
core   +1 more source

CITRIC ACID PRODUCTION BY Aspergillus niger REPEAT· BATCH CULTURE USING A . PRICKLY PEAR CACTUS EXTRACT MEDIUM [PDF]

Journal of Agricultural Chemistry and Biotechnology, 2003
The potential of prickly pear cactus extract as a fermentation medium for citric acid production by batch and repeat-batch cultures of Asp < /em>ergillus niger isolated from three locations of Aseer, Saudi Arabia was investigated.
Y. Mostafa, A. Al-Shehri,
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodinium cohnii

Microbial Cell Factories, 2020
Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity.
Liangsen Liu, Fangzhong Wang, Guangsheng Pei, Jinyu Cui, Jinjin Diao, Mingming Lv, Lei Chen, Weiwen Zhang   +7 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Investigation the effect of olive oil feeding strategies on Yarrowia lipolytica lipase production

Biological Journal of Microorganism, 2015
Introduction: Lipase of the yeast Yarrowia lipolytica used in detergents, cosmetics, pharmaceuticals and food industries. This enzyme production depends on medium composition, especially carbon source.  The purpose of this study was to investigate ...
Farshad Darvishi, Barumand Hosseini
doaj