Results 31 to 40 of about 43,933 (259)

Fault Diagnosis of Batch Reactor Using Machine Learning Methods

Modelling and Simulation in Engineering, 2014
Fault diagnosis of a batch reactor gives the early detection of fault and minimizes the risk of thermal runaway. It provides superior performance and helps to improve safety and consistency. It has become more vital in this technical era.
Sujatha Subramanian, Fathima Ghouse, Pappa Natarajan   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Group-Signature and Group Session Key Combined Safety Message Authentication Protocol for VANETs

IEEE Access, 2019
Anonymous authentication has significant contribution to privacy protection in safety message dissemination for Vehicular Ad Hoc Networks (VANETs); however, it suffers from heavy workload of vehicle revocation check and message signature verification ...
Chunhua Zhang, Xiaoping Xue, Lijuan Feng, Xin Zeng, Jingxiao Ma   +4 more
doaj   +1 more source

Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer

Scientific Reports, 2023
Human telomeres are linked to genetic instability and a higher risk of developing cancer. Therefore, to improve the dismal prognosis of pancreatic cancer patients, a thorough investigation of the association between telomere-related genes and pancreatic ...
Shengyang Chen, Shuiquan Hu, Baizhong Zhou, Bingbing Cheng, Hao Tong, Dongchao Su, Xiaoyong Li, Yanjun Chen, Genhao Zhang   +8 more
doaj   +1 more source

Identification of a Qualitative Signature for the Diagnosis of Dementia With Lewy Bodies

Frontiers in Genetics, 2021
Background and purpose: Diagnosis of dementia with Lewy bodies (DLB) is highly challenging, primarily due to a lack of valid and reliable diagnostic tools. To date, there is no report of qualitative signature for the diagnosis of DLB. We aimed to develop
Shu Zhou, Shu Zhou, Qingchun Meng, Lingyu Li, Luo Hai, Zexuan Wang, Zhicheng Li, Yingli Sun   +7 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A Secure and Efficient Data Integrity Verification Scheme for Cloud-IoT Based on Short Signature

IEEE Access, 2019
The Internet of Things (IoT) is also known as the Internet of everything. As an important part of the new generation of intelligent information technology, the IoT has attracted the attention both of researchers and engineers all over the world ...
Hongliang Zhu, Ying Yuan, Yuling Chen, Yaxing Zha, Wanying Xi, Bin Jia, Yang Xin   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source