Pharmacological inhibition of Bax-induced cell death: Bax-inhibiting peptides and small compounds inhibiting Bax [PDF]
Experimental Biology and Medicine, 2019 Bax is an essential mediator of mitochondria-dependent programed cell death. Bax belongs to the Bcl-2 family of proteins and its activities are regulated through interaction with other member proteins in the Bcl-2 family. To date, several apoptosis-inducing drugs activating Bax have been developed, and some of them are already in the market as ...
Kelsey, Jensen +4 more
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The Induction of Apoptosis by Resveratrol Through Regulatory Effect of miR-21 on the Gene Expression of Bcl2 and Bax in HCT-116 Cells [PDF]
Avicenna Journal of Medical Biochemistry, 2019 Background: Resveratrol (RezV) which is found in several plants including grapes and types of berries has a vital role in inducing apoptosis and suppressing cell proliferation.
Nooshin Shabab +2 more
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Effects of melatonin addition to the cold storage medium on cumulus oocyte complex apoptosis, viability and in vitro maturation rates of cat oocytes [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022 Usage of oocytes obtained from ovaries aft er long-term cold storage for in vitro embryo production is a promising tool for the protection of wildlife and endangered animal species. Mammalian oocytes are susceptible to oxidative stress with regard to the
Ramazan ARICI +13 more
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CONCURRENT EFFECT OF LINUM USITATISSIMUM AND EMBLICA OFFICINALIS ON LEAD INDUCED OXIDATIVE STRESS AND HISTOMORPHOLOGICAL CHANGES IN UTERUS OF FEMALE WISTAR RATS [PDF]
Exploratory Animal and Medical Research, 2022 Lead (Pb) is one of the oldest environmental contaminants and is well known to cause deleterious systemic effects on man and domestic animals including the reproductive system.
Amitava Paul, Karamala Sujatha
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اثر تمرینات مقاومتی به همراه مصرف عصارهی زعفران بر بیان ژنهای Bax، Bcl-2 و Caspase-3 در بافت هیپوکامپ رتهای نر آلزایمری القا شده [PDF]
مجله دانشکده پزشکی اصفهان, 2023 مقاله پژوهشیمقدمه: آلزایمر، یک بیماری مخرب با اختلالات پیشرونده است که با کاهش حافظه همراه و عدم وجود درمان قطعی برای آن میباشد، هدف از پژوهش حاضر، بررسی اثر تمرینات مقاومتی به همراه مصرف عصارهی زعفران بر بیان ژنهای Bax، Bcl-2 و Caspase-3 در بافت ...
فاضل بازیار +2 more
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The in vitro Effect of Doxorubicine-G2-FA Treatment on Breast Cancer Copyright [PDF]
Iranian Journal of Veterinary Medicine, 2020 BACKGROUND: To achieve delivery of a drug to tumors, folic acid (FA) was used as a targeting ligand to change nanocarriers. Since the folate receptor has more expression in several tumor types such as breast cancer. OBJECTIVES: The present study aimed to
Hamed Mansoor Lakooraj +4 more
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Effect of high-intensity interval training on expression of pro and anti-apoptotic genes in myocard tissue of aged male C57BL/6 mice [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2019 Purpose: Bax and BCL-2 genes are important genes that involve in the intrinsic pathway of apoptosis. Although the effects of interval and intensive exercises on the mechanisms involved in the gaining processes are less considered.
Rahman Soori +3 more
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World Journal of Traditional Chinese Medicine, 2022 Objective: The aim is to investigate the protective effect of andrographolide (AP) on retinal ganglion cells (RGC) in rats with glaucoma and its mechanism.
Jun Li, Jing Lu, Guang Chen, Dan Li
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Berberine induces apoptosis and arrests the cell cycle in multiple cancer cell lines
Archives of Medical Science, 2021 Introduction To examine the anti-cancer effects of berberine on multiple cancer cell lines, and to clarify the underlying molecular mechanisms. Material and methods The IC 50 values for the action of berberine on Tca8113 (oral squamous cell carcinoma),
Qian Li +3 more
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تأثیر تمرین هوازی با شدت متوسط و زیاد بر بیان ژنهای آپوپتوزی BAX (BCL2 associated X) و BCL2 (B-cell lymphoma 2) میوکارد موش صحرایی پس از کمخونی و خونرسانی مجدد [PDF]
فیزیولوژی ورزشی, 2020 هدف از انجام پژوهش حاضر، تعیین تأثیر تمرین هوازی با شدت متوسط و زیاد بر بیان ژنهای BAX و BCL2 میوکارد موشهای صحرایی نر پس از کمخونی و خونرسانی مجدد بود. در این پژوهش از 26 سر موش صحرایی ویستار دوماهه با وزن تقریبی 25/25 ± 25/225 گرم استفاده شد.
حامد علی زاده پهلوانی +5 more
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