Results 171 to 180 of about 144,672 (262)

Bevacizumab induces apoptosis in glioblastoma cells by upregulating miR-4695-5p to inhibit PKMYT1. [PDF]

RNA Biol
Shen Y, Yang C, Wang H, Hu S, Hao Y, Geng Y, Huang S.   +6 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Effect of Algal Lectin Siye on Proliferation and Apoptosis of Breast and Colon Cancer Cells. [PDF]

Mar Drugs
Zhang X, Ma J, Ma J, Xu T, Ruan X, Pang M, Wang T, Wang L.   +7 more
europepmc   +1 more source

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh, Eun‐Ryeong Hahm, Bruce L. Jacobs, Shivendra V. Singh   +3 more
wiley   +1 more source

Pretreatment of trans-ferulic acid improved neurotoxicity in a thioacetamide-induced hepatic encephalopathy rat model; participation of the MAPK/NF-κb signaling pathway. [PDF]

Front Pharmacol
Kilic AF, Suleyman B, Mammadov R, Bulut S, Mendil AS, Suleyman H.   +5 more
europepmc   +1 more source

A Potential Functional Food-Based Neuroprotective Strategy Using Mulberry Leaf Extract and Trolox Against H₂O₂-Induced Oxidative Stress in SH-SY5Y Cells. [PDF]

Foods
Mairuae N, Phanphak J, Thipboonchoo N, Wilaisit P, Butsamongkon P, Chotritthirong Y, Kaewbutra S, Loiklung C, Palachai N.   +8 more
europepmc   +1 more source

Pasteurella lipoprotein E interacts with host ABCF2 to facilitate adhesion and cell apoptosis

mLife, EarlyView.
Abstract Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (PlpE) of P. multocida contributed to bacterial adhesion to host cells.
Yuyao Shang, Fei Wang, Menghan Chen, Zihao Wang, Hanyuan Liu, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng   +8 more
wiley   +1 more source

Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids. [PDF]

Cell Rep
Zhang JS, Guy B, Santiago CP, Tiozzo C, Sreenath M, Chen YW, Blackshaw S, Johnston RJ.   +7 more
europepmc   +1 more source

Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1

Muscle &Nerve, EarlyView.
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno, Mohammad Nazim, Ruchen Zhang, Paniz Farshadyeganeh, Mikako Ito, Bisei Ohkawara   +5 more
wiley   +1 more source

Polycyclic aromatic hydrocarbon derivative 3-hydroxybenz[a]anthracene promotes the progression of T47D breast cancer cells by modulating relevant protein expression. [PDF]

Front Cell Dev Biol
Song W, Kang X, Li X, Yang Y, Wu X.
europepmc   +1 more source