Results 181 to 190 of about 144,754 (263)

Pasteurella lipoprotein E interacts with host ABCF2 to facilitate adhesion and cell apoptosis

mLife, EarlyView.
Abstract Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (PlpE) of P. multocida contributed to bacterial adhesion to host cells.
Yuyao Shang, Fei Wang, Menghan Chen, Zihao Wang, Hanyuan Liu, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng   +8 more
wiley   +1 more source

[<i>Qingda</i> Granules inhibit cerebral microvascular endothelial cell apoptosis in hypertensive mice by suppressing the P53 signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lin Y, Shi S, Wang J, Lin S, Zhang J, Lin S, Chen Y, Zhang L, Cai Q.   +8 more
europepmc   +1 more source

Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1

Muscle &Nerve, EarlyView.
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno, Mohammad Nazim, Ruchen Zhang, Paniz Farshadyeganeh, Mikako Ito, Bisei Ohkawara   +5 more
wiley   +1 more source

Avoiding Mitochondrial Apoptosis by the Bcl-2-Driven Bax Oligomerization on Membrane Surfaces. [PDF]

ACS Chem Biol
Ayscough SE, Clifton LA, Ådén J, Köhler S, Paracini N, Doutch J, Bragginton ÉC, Leung AE, Bogojevic O, Poon JF, Nagy TM, Wacklin-Knecht HP, Gröbner G.   +12 more
europepmc   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

Chrysoeriol-Mediated Neuroprotection in Parkinson's Disease in Mice: Targeting Apoptosis, α-Synuclein Accumulation, and Functional Recovery. [PDF]

Yale J Biol Med
Ali M, Mehreen M, Batool S, Khan S, Noor A, Mumtaz S, Zafar S.   +6 more
europepmc   +1 more source

Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice

PROTEOMICS, EarlyView.
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min, Choonseok Lee, Ravi Gupta, Gi Hyun Lee, Ji Soo Kim, Na Won Park, Joong Hyoun Chin, Ki‐Hong Jung, Sun Tae Kim   +8 more
wiley   +1 more source

A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function. [PDF]

Nat Commun
Gelles JD, Chen Y, Luna-Vargas MPA, Viacava Follis A, Al Noman MA, Kabir M, Bayiokos SG, Mohammed JN, Sebastian TM, Pham ND, Shi Y, Jin J, Kriwacki RW, Chipuk JE.   +13 more
europepmc   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source