Results 191 to 200 of about 144,672 (262)

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Retraction: Vitamin C and Turmeric Attenuate Bax and Bcl-2 Proteins' Expressions and DNA Damage in Lead Acetate-Induced Liver Injury. [PDF]

Dose Response
europepmc   +1 more source

Sildenafil pretreatment attenuates apoptosis and intestinal injury in a hypoxia-ischemia-induced NEC-like rat model. [PDF]

Sci Rep
Kurtuluş Ş, Öztopuz Ö, Karaboğa İ, Aylanç H.   +3 more
europepmc   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

Avoiding Mitochondrial Apoptosis by the Bcl-2-Driven Bax Oligomerization on Membrane Surfaces. [PDF]

ACS Chem Biol
Ayscough SE, Clifton LA, Ådén J, Köhler S, Paracini N, Doutch J, Bragginton ÉC, Leung AE, Bogojevic O, Poon JF, Nagy TM, Wacklin-Knecht HP, Gröbner G.   +12 more
europepmc   +1 more source

Perinatal Post‐Anoxic Spinal Cord Injury: A Barrier to Pallidal Neuromodulation? About 2 Cases

Movement Disorders Clinical Practice, EarlyView.
Marylou Grasso, Cassandra Coelho, Emilie Chan‐Seng, Philippe Coubes, Gaëtan Poulen   +4 more
wiley   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, EarlyView.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons

Biology Open
Catherine L. Kaminski, Debarghya Dutta Banik, Ligia B. Schmitd, Brian A. Pierchala   +3 more
doaj   +1 more source

A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function. [PDF]

Nat Commun
Gelles JD, Chen Y, Luna-Vargas MPA, Viacava Follis A, Al Noman MA, Kabir M, Bayiokos SG, Mohammed JN, Sebastian TM, Pham ND, Shi Y, Jin J, Kriwacki RW, Chipuk JE.   +13 more
europepmc   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source