Results 221 to 230 of about 197,763 (291)

Long-Term Impact of Early-Life Stress on Hippocampal Apoptotic Gene Expression in BALB/c Mice. [PDF]

Neurochem Res
Barokah AN, Gürsoy İK, Dönmez MH, Fitremann J, Bayram A, Bayram KK.   +5 more
europepmc   +1 more source

Bax, Nicholas

core  

DARS2 Promotes Tumorigenesis and Metastasis by Activating PI3K/Akt/GSK‐3β/β‐Catenin Signaling Pathway in Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast cancer (BC) is poorly understood.
Na Wang, Ming Huang
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

Simultaneous induction of differentiation and senescence in cardiac fibroblasts by TGF-β1: effects of senotherapeutics drugs. [PDF]

Front Pharmacol
Espinoza-Perez C, Osorio JM, Vélez R, Ortega Bustos J, Machuca V, Rivas S, Sánchez-Ferrer CF, Peiró C, Vivar R, Díaz-Araya G.   +9 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Mechanism of claudin-2 in RTECs apoptosis after renal obstruction. [PDF]

Urolithiasis
Zhao D, Tang G, Hu G, Zeng L, Su W, Tang J.   +5 more
europepmc   +1 more source

Ophiobolin A Induces an Apoptotic Transcriptional Signature and Modulates Redox Homeostasis in T98G and U118MG Glioblastoma Cells: A Machine Learning Approach. [PDF]

Int J Mol Sci
Woźnicki P, Hudy D, Trzaskoś O, Avijit P, Xavierselvan M, Tabarkiewicz J, Strzelczyk JK, Aebisher D.   +7 more
europepmc   +1 more source

<i>Ginkgo biloba</i> Extract Inhibits Cisplatin-Induced Acute Kidney Injury-to-Chronic Kidney Disease Through Downregulating Apoptosis Mediated by the HIF-1α/Phosphatidylinositol Pathway. [PDF]

Curr Issues Mol Biol
Xu W, Huang J, Chen S, Yang Y, Wan P, Chen X, Ye X, Huang S.   +7 more
europepmc   +1 more source