Results 131 to 140 of about 150,507 (294)

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

open access: yesInterdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen   +12 more
wiley   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

open access: yesJCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan   +4 more
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran   +5 more
wiley   +1 more source

Optogenetic engineering of BAX to control mitochondrial permeabilization and attenuate apoptosis in cells. [PDF]

open access: yesExp Mol Med
Lee D   +11 more
europepmc   +1 more source

JNK promotes Bax translocation to mitochondria through phosphorylation of 14‐3‐3 proteins [PDF]

open access: bronze, 2004
Fuminori Tsuruta   +8 more
openalex   +1 more source

Using machine learning to predict clinical remission with exclusive enteral nutrition in pediatric Crohn disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Exclusive enteral nutrition (EEN) is a first‐line treatment for induction of remission in luminal pediatric Crohn disease (pCD). However, as the efficacy of EEN varies from patient to patient, there is a need to distinguish between responders and nonresponding patients. This study had two aims.
Ricardo G. Suarez Suarez   +22 more
wiley   +1 more source

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