Results 161 to 170 of about 150,507 (294)

Integrated In Silico and In Vitro Study of Copper Nanocatalyzed Carbonyl-Functionalized Triazoles-Inducing S Phase Cell Cycle Arrest and Apoptosis in MCF-7. [PDF]

ChemistryOpen
Mondal J, Dasgupta T, Kumar CK, Nandagopal PB, Mal S, Paul S, S A, Pandya C, Emerson IA, Manickam V, Sivaramakrishna A.   +10 more
europepmc   +1 more source

Immunohistochemical Study for Expression of p53, bcl-2 and Bax in Uterine Sarcoma [PDF]

, 1997
Hyung Sik Chu, Jong Hyeok Kim, Jooryung Huh, So Dug Lim, Jun Hee Na, Chang Won Koh, Yong Man Kim, Young Tak Kim, Joo‐Hyun Nam, Jung Eun Mok   +9 more
openalex   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Melatonin Reduces Radiation-induced Apoptosis Through Change of bax and bcl-2 Expression in Peripheral Blood Lymphocytes. [PDF]

Adv Biomed Res
Motallebzadeh E, Talaei SA, Mohseni M.
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies. [PDF]

Cancer Innov
Hossain MS, Khatun S, Mia MM, Zohora F, Sarker MR, Tanjida Islam KM, Sayeed MA, Mou MA, Hamidu S, Hamidu F, Wasaf Hasan AM, Mumtaj S, Hossain MK, Sohel M.   +13 more
europepmc   +1 more source

Expression of Apoptosis, Bax and Bcl-2 in Nasal Polyps

, 2005
Il-Gyu Kang, Yu-Jin Hwang, Jong-Su Ha, Dong-Gyu Kim, Seon-Tae Kim   +4 more
openalex   +2 more sources

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, EarlyView.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source

Hypoxic Small Extracellular Vesicle Preconditioning of AC16 Cardiomyocytes Increase Caspase-3 and Caspase-8 Activity During Hypoxia. [PDF]

Int J Mol Sci
Røsand Ø, Johansen V, Marwarha G, Høydal MA.   +3 more
europepmc   +1 more source

Antibacterial and anticancer activities of biosynthesized silver nanoparticles using Artemisia khorassanica extract: Bax and Bcl2 apoptosis gene expression analysis

, 2018
Shila Rashidian, Aliasghar bagheri Keshtli, Amir Mirzaie   +2 more
openalex   +1 more source