Results 11 to 20 of about 298,121 (314)
Redox Report, 2021 Background Progression of Benign Prostate hyperplasia (BPH) is vulnerable to oxidative stress (OS) and prostatic enlargement among the aging males through apoptosis deregulation.
Nabila Jahan +5 more
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Armeniacae Semen Regulates Apoptosis and Cell Cycle Progression in MCF-7, MDA-MB-231, and T47D Breast Cancer Cell Lines [PDF]
Middle East Journal of Cancer, 2021 Background: Amygdalin is a glycoside ingredient of rosacea plants that exerts an antitumor effect by blocking the growth of the tumor cells. Therefore, we aimed to use the Armeniacae semen, a member of the Rosacea family, which contains a large amount of
Shiva Mosadegh Manshadi +2 more
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Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
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Nature, 2008 Apoptotic cell death is an intricate and highly regulated process. To initiate apoptosis, the protein BIM binds to a hitherto unrecognized site on the BAX protein to trigger permeabilization of the outer mitochondrial membrane.
Jerry E. Chipuk, Douglas R. Green
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Berberine induces apoptosis and arrests the cell cycle in multiple cancer cell lines
Archives of Medical Science, 2021 Introduction To examine the anti-cancer effects of berberine on multiple cancer cell lines, and to clarify the underlying molecular mechanisms. Material and methods The IC 50 values for the action of berberine on Tca8113 (oral squamous cell carcinoma),
Qian Li +3 more
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Mitochondrial neurogastrointestinal encephalomyopathy: approaches to diagnosis and treatment [PDF]
, 2020 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disease caused by mutations in TYMP, the gene encoding for the enzyme thymidine phosphorylase.
Bax, BE
core +1 more source
Pharmacological inhibition of Bax-induced cell death: Bax-inhibiting peptides and small compounds inhibiting Bax [PDF]
Experimental Biology and Medicine, 2019 Bax is an essential mediator of mitochondria-dependent programed cell death. Bax belongs to the Bcl-2 family of proteins and its activities are regulated through interaction with other member proteins in the Bcl-2 family. To date, several apoptosis-inducing drugs activating Bax have been developed, and some of them are already in the market as ...
Kelsey Jensen +4 more
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The Anti-apoptosis Effects of Daidzein in the Brain of D-Galactose Treated Mice
Molecules, 2007 The purpose of this study was to explore the neuroprotective effects of daidzein on the apoptotic pathway in the hippocampus and cortex of D-galactose treated mice. For this purpose we have examined the expression of bcl-2 mRNA, bax mRNA and caspase-3 in
Xiang-bin Hu +6 more
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Role of microRNA-124-3p/Bax axis in neonatal hypoxic-ischaemic encephalopathy
Biotechnology & Biotechnological Equipment, 2020 Neonatal hypoxic-ischaemic encephalopathy (HIE) is a neurological disease that can cause neonatal death. MicroRNA-124-3p (miR-124-3p) plays an important role in the development of various diseases.
Aiju Chen +3 more
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A Novel Mechanism for CTCF in the Epigenetic Regulation of Bax in Breast Cancer Cells [PDF]
, 2013 Wepreviously reported the association of elevated levels of themultifunctional transcription factor, CCCTC binding factor (CTCF), in breast cancer cells with the specific anti-apoptotic function of CTCF.
Abramoff +68 more
core +3 more sources