Results 221 to 230 of about 198,180 (297)

Bax, Nicholas

core  

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Beraprost Attenuates Starvation-Induced Apoptosis and Protects Feline Endothelial Cells. [PDF]

Vet Med Sci
Matsuura T, Marasigan CNBB, Yonezawa T.
europepmc   +1 more source

Bax, DV

, 2016
Bax, DV
core  

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Postnatal Day 7 Ethanol Exposure is Associated with Apoptosis-Related Changes in GAD67-Positive Neurons and Candidate CaMKII/GSK-3β/BAX Signaling in the Mouse Spinal Dorsal Horn. [PDF]

Subst Abuse Rehabil
Wang Y, Cheng Z, Wang Z, Ding X, Xu X, Sun S, Zheng Y, Liu M, Xu J, Nan X, Xu J, Li X, Ren Z, Zhang K.   +13 more
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Caffeic Acid Mitigates L-Methionine-Induced Impairment of Hippocampal Neural Stem Cells Through Anti-Apoptotic Signaling in Adult Rats. [PDF]

Biology (Basel)
Dornlakorn O, Sritawan N, Prajit R, Sirichoat A, Wigmore P, Welbat JU.   +5 more
europepmc   +1 more source

Protective Effects of Lactobacillus-Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli-Infected Rats. [PDF]

Vet Med Sci
Sedghi S, Keshtmand Z, Hosseini S.
europepmc   +1 more source