Effect of N-acetyl cysteine on oxidative stress and Bax and Bcl2 expression in the kidney tissue of rats exposed to lead [PDF]
The Ukrainian Biochemical Journal, 2021 This study aimed to consider the lead-induced oxidative damage of the kidney of male rats and the role of antioxidant N-acetylcysteine (NAC) in preserving cells against Pb toxicity.
M. Gholami +4 more
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Armeniacae Semen Regulates Apoptosis and Cell Cycle Progression in MCF-7, MDA-MB-231, and T47D Breast Cancer Cell Lines [PDF]
Middle East Journal of Cancer, 2021 Background: Amygdalin is a glycoside ingredient of rosacea plants that exerts an antitumor effect by blocking the growth of the tumor cells. Therefore, we aimed to use the Armeniacae semen, a member of the Rosacea family, which contains a large amount of
Shiva Mosadegh Manshadi +2 more
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Curcumin as an anti-proliferative agent in breast cancer through RASSF1A, Bax, and caspase-3 protein
Сибирский онкологический журнал, 2023 Background. Curcumin is a polyphenol that has pharmacological activity that can inhibit tumor cell growth and induce apoptosis through various mechanisms. However, the specifc mechanism of curcumin cytotoxicity remains controversial because of many anti-
N. A. Rahmah +8 more
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Неотложная медицинская помощь, 2022 Restenosis of the reconstruction zone is one of the main postoperative complications of vascular reconstructions, which develops in 18–40% of cases and leads to an increase in the risk of limb loss to 20–25%. The search for new markers for predicting the
R. E. Kalinin +3 more
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IFI27 and BAX are Essential for GSDME-Mediated Myeloma Cell Pyroptosis. [PDF]
Adv Sci (Weinh)The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Cui Y +12 more
europepmc +2 more sources
Apoptosis as a potential target to arrest and survival of hydatid cyst
Advanced Biomedical Research, 2023 Background: Hydatidosis is a serious and life-threatening disease that may lead to the death of the host if diagnosed and treated improperly. Apoptosis has been investigated as a mechanism of host innate immunity in suppressing parasites and also the ...
Maryam Rahmani-Dehaghani +3 more
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Frontiers in Pharmacology, 2023 Background: Herbs originating from the Aconitum L. (Ranunculaceae), such as Aconitum carmichaelii Debeaux. (Wutou), Aconitum pendulum Busch. (Tiebangchui), and Aconitum kusnezoffii Reichb. (Caowu), etc.
Gelin Xiang +7 more
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Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Humic acid (HA) and Fulvic acid (FA) are major members of humic substances, which are extracted from organic sources including soil and peat.
Mitra Salehi +4 more
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Assessment of the effect of CoFe2O4@Ag synthesized by Spirulina platensis on colon cancer cell line and evaluation the expression of BAX and Bcl-2 genes [PDF]
Journal of Epigenetics, 2023 : Colorectal cancer is a common cancer in both men and women. Colorectal cancer is the third widely diagnosed cancer in the world. The emergence of nanotechnology led the researchers to introduce novel nano-products for cancer diagnosis and treatment ...
Zahra Pouresmaeil +2 more
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Interaction between Bax and Bcl-XL proteins confirmed by partial acceptor photobleaching-based FRET imaging [PDF]
Journal of Innovative Optical Health Sciences, 2020 Exact interaction mechanism between Bax and Bcl-XL, two key Bcl-2 family proteins, is an interesting and controversial issue. Partial acceptor photobleaching-based quantitative fluorescence resonance energy transfer (FRET) measurement, PbFRET, is a ...
Fangfang Yang +3 more
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