Results 111 to 120 of about 145,032 (262)

2-Pyrazoline-5-One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells. [PDF]

J Biochem Mol Toxicol
Sevinc SK, Küçükgüzel ŞG, Rollas S, Yukcu F.   +3 more
europepmc   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Reverse engineering of BNIP3 identifies a mitochondrial protective peptide. [PDF]

Nat Commun
Hendgen-Cotta UB, Roth A, Beuck C, Messiha D, Settelmeier S, Shah SB, Korste S, Bravo-Rodriguez K, Blueggel M, Cansiz F, Martins Nascentes Melo L, Roesler J, Meckelmann SW, Schmitz OJ, Kaschani F, Kaiser M, Esfeld S, El Bounkari O, Bernhagen J, Brameyer S, Jung K, Schmitt LI, Leo M, Hagenacker T, Totzeck M, Minor T, Ehrmann M, Tasdogan A, Bayer P, Rassaf T.   +29 more
europepmc   +1 more source

Stabbed in the BAX [PDF]

Nature, 2008
Douglas R. Green, Jerry E. Chipuk
openaire   +1 more source

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh, Andrew Cooke, Harshal Soni, Susan Liu, Mamadou Bah, Brianna Bellis, Laura Smith, Michael Capaldi, Nicholas Levy, Erik Wilhelm, Kristopher Barnthouse   +10 more
wiley   +1 more source

Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review. [PDF]

Health Sci Rep
Tanisha MH, Siddique MA, Ahmed Z, Mustafa N, Tasneem F.   +4 more
europepmc   +1 more source

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons

Biology Open
Catherine L. Kaminski, Debarghya Dutta Banik, Ligia B. Schmitd, Brian A. Pierchala   +3 more
doaj   +1 more source

FABP3 Aggravates Cerebral Ischemia-Reperfusion Injury by Promoting Mitochondrial Lipid Accumulation and Enhancing BAX-Dependent Apoptosis. [PDF]

Cells
Zheng Y, Luo A, Fukunaga K, Liu Q, Guo Q.   +4 more
europepmc   +1 more source

Bax to Bak [PDF]

Nature Reviews Molecular Cell Biology, 2001
openaire   +1 more source