Results 121 to 130 of about 145,032 (262)

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

BMEMat, EarlyView.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan, Yuchan Xue, Miao Zhang, Zihao Zhang, Shiyu Peng, Minghao Sui, Han Ding, Yingying Nie, Yuemin Feng, Le Wang, Tianru Zhang, Mingchuan Yu, He Xia, Hong Liu, Qiang Zhu, Songbo Zhao   +15 more
wiley   +1 more source

Upregulation of a Circular <i>BAX</i> Transcript in Breast Cancer Is Associated with Unfavorable Prognosis. [PDF]

Int J Mol Sci
Stafyla VK, Christodoulou S, Tsiakanikas P, Michalopoulos N, Danias N, Kokoropoulos P, Kontos CK, Arkadopoulos N.   +7 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Ubiquitin-Specific Protease 49 Interacts with Bax to Modulate Apoptosis. [PDF]

Int J Mol Sci
Choi HS, Kim SY, Kim SR, Baek KH.
europepmc   +1 more source

Structure of Bax [PDF]

Cell, 2000
Suzuki, Motoshi, Youle, Richard J., Tjandra, Nico   +2 more
openaire   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Molecular Docking of Phytochemicals Involved in Apoptotic Pathway and Their Interactions with <i>CASP3</i>, <i>CASP9</i>, and <i>BAX</i> in HepG2 Cell Line. [PDF]

Plants (Basel)
Younas M, Zubair M, Yousaf Shani M, Ahmad S, Arshad I, Jarecki W, Azmat M, Farid G, Yasin Ashraf M, Zhu L.   +9 more
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Hyperbaric Oxygen Exposure During the Holding Phase Modulates Early Apoptotic Signaling in Hair Grafts: A Molecular Pilot Study. [PDF]

Clin Cosmet Investig Dermatol
Sahan A, Simsek G, Akyurek ME, Kucun MK, Erol SS, Arslan S.   +5 more
europepmc   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source