Results 131 to 140 of about 103,187 (313)

Unifying Composition and Process Design: A Heterogeneous Graph Neural Network for Discovering High‐Performance Cu Alloys

open access: yesAdvanced Science, EarlyView.
By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin   +12 more
wiley   +1 more source

DPpackage: Bayesian Semi- and Nonparametric Modeling in R [PDF]

open access: yes
Data analysis sometimes requires the relaxation of parametric assumptions in order to gain modeling flexibility and robustness against mis-specification of the probability model.
Fernando A. Quintana   +4 more
core   +1 more source

Euphorbia Bayesian phylogenetic tree [PDF]

open access: yes, 2019
50% majority rule consensus tree from Bayesian analysis of 11587 bps of DNA markers spanning all three plant genomes: chloroplast, mitochondrial ...
van der Hooft, Justin J. J.   +15 more
core   +1 more source

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

open access: yesAdvanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok   +4 more
wiley   +1 more source

Multi-test Decision Tree and its Application to Microarray Data Classification [PDF]

open access: yes, 2014
Objective: The desirable property of tools used to investigate biological data is easy to understand models and predictive decisions. Decision trees are particularly promising in this regard due to their comprehensible nature that resembles the ...
Marcin Czajkowski   +5 more
core   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

Discriminant analysis and machine learning approach for evaluating and improving the performance of immunohistochemical algorithms for COO classification of DLBCL

open access: yesJournal of Translational Medicine, 2019
Background Diffuse large B-cell lymphoma (DLBCL) is classified into germinal center-like (GCB) and non-germinal center-like (non-GCB) cell-of-origin groups, entities driven by different oncogenic pathways with different clinical outcomes.
Yocanxóchitl Perfecto-Avalos   +14 more
doaj   +1 more source

MAPTree: Beating “Optimal” Decision Trees with Bayesian Decision Trees

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
Decision trees remain one of the most popular machine learning models today, largely due to their out-of-the-box performance and interpretability. In this work, we present a Bayesian approach to decision tree induction via maximum a posteriori inference of a posterior distribution over trees.
Colin Sullivan   +2 more
openaire   +2 more sources

Bayesian evaluation of the southern hemisphere radiocarbon offset during the holocene [PDF]

open access: yes, 2009
While an interhemispheric offset in atmospheric radiocarbon levels from AD 1950–950 is now well established, its existence earlier in the Holocene is less clear, with some studies reporting globally uniform 14C levels while others finding Southern ...
Turney, Chris S.M.   +8 more
core   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

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