Results 41 to 50 of about 116,763 (266)

Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination

Advanced Science, 2022
Blood–brain barrier (BBB) impairment is an early prevalent feature of multiple sclerosis (MS), and remains vital for MS progression. Microglial activation precedes BBB disruption and cellular infiltrates in the brain of MS patients.
Zhongwang Yu, Xue Fang, Weili Liu, Rui Sun, Jintao Zhou, Yingyan Pu, Ming Zhao, Dingya Sun, Zhenghua Xiang, Peng Liu, Yuqiang Ding, Li Cao, Cheng He   +12 more
doaj   +1 more source

Patterns and drivers of the belowground bud bank in alpine grasslands on the Qinghai-Tibet Plateau

Frontiers in Plant Science, 2023
IntroductionIn grassland ecosystems dominated by asexual plants, the maintenance, renewal, and resistance of plant populations to disturbance are more dependent on the belowground bud bank (BBB).
Wencheng Li, Wencheng Li, Wencheng Li, Wencheng Li, Aiping Huang, Aiping Huang, Tiancai Zhou, Miao Liu, Sujie Ma, Sujie Ma, Ningning Zhao, Ningning Zhao, Xiangtao Wang, Xiangtao Wang, Jian Sun   +14 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

The prevalence and factors associated for anti-tuberculosis treatment non-adherence among pulmonary tuberculosis patients in public health care facilities in South Ethiopia: a cross-sectional study

BMC Public Health, 2017
Background Evidence exists pointing out how non-adherence to treatment remains a major hurdle to efficient tuberculosis control in developing countries.
Tadele Teshome Woimo, Wondwossen Kassahun Yimer, Temesgen Bati, Hailay Abrha Gesesew   +3 more
doaj   +1 more source

On the degeneration of étale $\Bbb Z/p\Bbb Z$ and $\Bbb Z/p^2\Bbb Z$-torsors in equal characteristic $p>0$

Hiroshima Mathematical Journal, 2007
Let $R$ be a complete discrete valuation ring of equal characteristic $p>0$. In this paper we investigate finite and flat morphisms $f:Y\to X$ between formal $R$-schemes which have the structure of an etale $\Bbb Z/p^n\Bbb Z$-torsor above the generic fiber of $X$, for $n=1,2$, with some extra geometric conditions on $X$ and $Y$.
openaire   +2 more sources

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu, Xin Yu, Jingtong Li, Chunyang Zheng, Yukang Zhang, Mingyu Jia, Tan Tian, Weiwei Zheng, Pinghui Zhou, Yingji Mao   +9 more
wiley   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

OBJECTIVE METHODS FOR DETERMINE THE SEVERITY AND PROGNOSIS OF PERINATAL HYPOXIC-ISCHEMIC CNS

Акушерство, гинекология и репродукция, 2016
Perinatal hypoxic-ischemic damage of the CNS is a major cause of mortality and neonatal incapacitating. The severity and prognosis is not always possible to accurately determine by clinical and tools methods of examination.
D. V. Blinov
doaj  

Mechanisms of Astrocyte Action in the Blood Brain Barrier: From Structural Support to Dynamic Regulation

Journal of Integrative Neuroscience
The blood-brain barrier (BBB) consists of endothelial cells enmeshed by brain microvessels, surrounding basement membrane, pericytes and astrocyte pedicles.
Di Feng, Lili Wang, Aoyu Hu, Shanshan Zhang   +3 more
doaj   +1 more source

“Build back better” approach to disaster recovery: Research trends since 2006

Progress in Disaster Science, 2019
The “build back better” (BBB) approach to disaster recovery was first introduced in 2006 by the United Nations Secretary-General's Special Envoy for Tsunami Recovery, former US President William Clinton.
Glenn Fernandez, Iftekhar Ahmed
doaj   +1 more source