Results 31 to 40 of about 16,116 (171)

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth. [PDF]

PLoS ONE, 2013
Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a long history of uses for the treatment of multiple diseases, including cancers.
Lingyi Fu, Wangbing Chen, Wei Guo, Jingshu Wang, Yun Tian, Dingbo Shi, Xiaohong Zhang, Huijuan Qiu, Xiangsheng Xiao, Tiebang Kang, Wenlin Huang, Shusen Wang, Wuguo Deng   +12 more
doaj   +1 more source

Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota

Journal of Pharmaceutical Analysis, 2021
Berberine (BBR) is an isoquinoline alkaloid extracted from Coptis chinensis that improves diabetes, hyperlipidemia and inflammation. Due to the low oral bioavailability of BBR, its mechanism of action is closely related to the gut microbiota.
Zheng-Wei Zhang, Lin Cong, Ran Peng, Pei Han, Shu-Rong Ma, Li-Bin Pan, Jie Fu, Hang Yu, Yan Wang, Jian-Dong Jiang   +9 more
doaj   +1 more source

Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy

Frontiers in Immunology, 2022
Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long history of treating dysentery in the clinic. Over the past two decades, the polytrophic, pharmacological, and biochemical properties of BBR have been intensively ...
Cuipeng Zhu, Kaiqi Li, Xiao-Xu Peng, Tong-Jia Yao, Zi-Yu Wang, Ping Hu, Demin Cai, Hao-Yu Liu, Hao-Yu Liu   +8 more
doaj   +1 more source

BBR- BrazilianBusiness Review: Evolução editorial-científica apoiada em tecnologia

, 2019
Apresentação da BBR no Painel EPQ4 Enanpad Inovação na Editoração de ...
Mainardes, Emerson Wagner, Mainardes, Emerson Wagner (8314380)   +1 more
core   +1 more source

PEG–lipid–PLGA hybrid nanoparticles loaded with berberine–phospholipid complex to facilitate the oral delivery efficiency

Drug Delivery, 2017
The natural product berberine (BBR), present in various plants, arouses great interests because of its numerous pharmacological effects. However, the further development and application of BBR had been hampered by its poor oral bioavailability.
Fei Yu, Mingtao Ao, Xiao Zheng, Nini Li, Junjie Xia, Yang Li, Donghui Li, Zhenqing Hou, Zhongquan Qi, Xiao Dong Chen   +9 more
doaj   +1 more source

Requirement for Ergosterol in Berberine Tolerance Underlies Synergism of Fluconazole and Berberine against Fluconazole-Resistant Candida albicans Isolates

Frontiers in Cellular and Infection Microbiology, 2017
Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C.
Yi Xu, Hua Quan, Hua Quan, Yan Wang, Hua Zhong, Jun Sun, Jianjiang Xu, Nuan Jia, Yuanying Jiang   +8 more
doaj   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source

Behavior of Stone Mastic Asphalt at Low Temperatures

Romanian Journal of Transport Infrastructure
This paper presents a detailed analysis of the influence of bitumen on low-temperature cracking of MAS 16 asphalt mixtures (stone mastic asphalt) used as wearing course on heavily trafficked roads.
Daniela Dermengiu Roxana, Carmen Răcănel, Mihai Dicu   +2 more
doaj   +1 more source

Constructing and Validating New County‐Level Cultural Capital Indices for Applied Policy Analysis: Evidence From SNAP Take‐Up

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Cultural capital influences a wide range of social and economic outcomes, yet quantitative measures suitable for policy analysis remain limited. We develop county‐level cultural capital indices for the US based on Bourdieu's framework of objectified, embodied, and institutionalized cultural capital.
Pratyoosh Kashyap, Becca B. R. Jablonski, John Bovay   +2 more
wiley   +1 more source

Effect of nano-TiO2 on physical and rheological properties of asphalt cement

Open Engineering
In recent years, nano-modified asphalt has gained significant attraction from researchers in the design of asphalt pavement fields. The recently discovered Titanium dioxide nanoparticles (TiO2) are among the most exciting and promising nanomaterials ...
Mohammed Ahmed Mahir, Abed Alaa H.
doaj   +1 more source