Results 11 to 20 of about 5,522 (115)
Structure of face-centred icosahedral quasicrystals with cluster close packing. [PDF]
Acta Crystallogr A Found AdvUsing higher‐dimensional crystallography, a new 6D structure model is proposed for F‐type icosahedral quasicrystals with cluster close packing.A 6D structure model for face‐centred icosahedral quasicrystals consisting of so‐called pseudo‐Mackay and mini‐Bergman‐type atomic clusters is proposed based on the structure model of the Al69.1Pd22Cr2.1Fe6.8 3 ...
Yamada T, Takakura H, Yamamoto A.
europepmc +2 more sources
Recent Insights in Multi-Target Drugs in Pharmacology and Medicinal Chemistry. [PDF]
ChemMedChemThis review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Cemali SH +7 more
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Gene Expression, Docking and Machine Learning in Malaria Drug Discovery: A Systematic Review. [PDF]
Biochem Res IntBackground Malaria remains a significant and worldwide health threat with increasing resistance to current treatments, stimulating the demand for innovative approaches in pursuing drug discovery. This systematic review integrates the progress made from 2014 through 2024 regarding molecular methods like gene expression profiling, molecular docking and ...
Dangana RS +4 more
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Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues. [PDF]
Immunol RevABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Olson EC, Williams A, Eisenbarth SC.
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Long non-coding RNAs as key regulators of neurodegenerative protein aggregation. [PDF]
Alzheimers DementAbstract The characteristic events in neurodegenerative diseases (NDDs) encompass protein misfolding, aggregation, accumulation, and their related cellular dysfunction, synaptic function loss. While distinct proteins are implicated in the pathological processes of different NDDs, the process of protein misfolding and aggregation remains notably similar
Xu Q, Liu D, Zhu LQ, Su Y, Huang HZ.
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Analytical Frameworks and Theories of Electric Power in Non‐Linear Circuits
IET Generation, Transmission &Distribution, Volume 20, Issue 1, January/December 2026.Based on the challenges of distorted currents and non‐linear components in modern power grids, this article reviews seminal electrical power theories that seek to generalize the traditional definitions of active, reactive, and apparent power. It provides a detailed analysis of their mathematical foundations, practical implementation, and validity.
Rafael Escudero, Luis Ibarra
wiley +1 more source
Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection
Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.Pathogen detection is crucial for preventing and managing health risks. This review consolidates the selection of functional nucleic acids (FNAs) for pathogen detection and the development of cost‐effective, simple diagnostic applications. It focuses on integrating FNAs with gold nanoparticles, polydiacetylenes, protein enzymes, G‐quadruplexes, and ...
Rudi Liu +3 more
wiley +2 more sources
The Significance of Informal Logic for Philosophy
Informal Logic, 2000 Informal logic is a new sub-discipline of philosophy, roughly definable as the philosophy of argument. Contributors have challenged the traditional concept of an argument as a premiss-conclusion complex, in favour of speech-act, functional and dialogical
David Hitchcock
doaj +1 more source
The Thomas-Nolt Dispute: Some Lessons about Induction
Informal Logic, 1999 I resolve an apparently unresolved dispute about how probable uniform experience makes an extrapolation from it, and draw some general lessons about such enumerative induction.
David Hitchcock
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Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Glia, Volume 73, Issue 12, Page 2464-2482, December 2025.Main Points Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz +9 more
wiley +1 more source