Results 191 to 200 of about 18,005 (233)
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Administration of granulated BCAA and quality of life
Hepatology Research, 2004The PEM (protein energy malnutrition) is an important factor for improvement of prognosis and QOL in the patients with liver cirrhosis. In 453 chronic liver disease patients, QOL decreased significantly according to the progression of disease assessed by SF-36 (Kruskal-Wallis test ...
Naohiro Kawamura
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Dietary Pattern and Plasma BCAA-Variations in Healthy Men and Women—Results from the KarMeN Study [PDF]
Nutrients, 2018 Branched-chain amino acids (BCAA) in plasma are discussed as risk factors for the onset of several diseases. Information about the contribution of the overall diet to plasma BCAA concentrations is controversial.
Lara Frommherz, Achim Bub, Benedikt Merz
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Overtraining and the BCAA hypothesis
Medicine & Science in Sports & Exercise, 1998The purpose of this review was to give an answer to the question whether there are convincing data to support the hypothesis of an amino acid imbalance as one possible mechanism to explain overtraining syndrome. Animal studies point to an enhanced synthesis of the neurotransmitter 5-hydroxytryptamine through an amino acid imbalance at the blood-brain ...
U A, Gastmann, M J, Lehmann
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How to select BCAA preparations
Hepatology Research, 2004In Japan, oral branched-chain amino acid (BCAA) preparations are used in nutritional therapy for correcting disorders of protein and amino acid metabolism in patients with liver cirrhosis. There are two forms of oral BCAA preparations: enteral nutrition products for liver failure (or elemental nutrition products for liver cirrhosis) and oral BCAA ...
Akinobu, Kato, Kazuyuki, Suzuki
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Effect of metformin on myotube BCAA catabolism
Journal of Cellular Biochemistry, 2019AbstractMetformin has antihyperglycemic properties and is a commonly prescribed drug for type II diabetes mellitus. Metformin functions in part by activating 5′‐AMP‐activated protein kinase, reducing hepatic gluconeogenesis and blood glucose. Metformin also upregulates peroxisome proliferator‐activated receptor‐gamma coactivator‐1α (PGC‐1α).
Madison E. Rivera +2 more
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Give and take: competition for BCAAs in the tumour microenvironment
Nature Metabolism, 2020Pancreatic adenocarcinoma (PDAC) is often characterized by substantial amounts of fibrosis, and how these stromal components affect metabolite availability is not fully understood. Zhu et al. now show that cancer-associated fibroblasts consume branched-chain amino acids (BCAAs) at high levels but release corresponding branched-chain α-ketoacids that ...
Russell E. Ericksen, Weiping Han
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BCAA Metabolism and NH3 Homeostasis
2016The branched chain amino acids (BCAA) are essential amino acids required not only for growth and development, but also as nutrient signals and as nitrogen donors to neurotransmitter synthesis and glutamate/glutamine cycling. Transamination and oxidative decarboxylation of the BCAAs are catalysed by the branched-chain aminotransferase proteins (BCATm ...
M E, Conway, S M, Hutson
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Medicine & Science in Sports & Exercise, 1999
The purpose of this study was to assess the effects of pre-exercise administration of branched-chain amino acids (BCAA), glucose, and glucose plus BCAA on time to exhaustion during treadmill exercise in rats.Wistar rats were injected intraperitoneally with 1 mL of saline (0.9% NaCl), BCAA (30 mg), glucose (100 mg), or glucose plus BCAA 5 min before ...
P, Calders +3 more
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The purpose of this study was to assess the effects of pre-exercise administration of branched-chain amino acids (BCAA), glucose, and glucose plus BCAA on time to exhaustion during treadmill exercise in rats.Wistar rats were injected intraperitoneally with 1 mL of saline (0.9% NaCl), BCAA (30 mg), glucose (100 mg), or glucose plus BCAA 5 min before ...
P, Calders +3 more
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2015
The three branched chain amino acids are unique in that the first catabolic step does not occur in the liver. Leucine, isoleucine, and valine share the first two catabolic enzymes—branched chain aminotransferase (BCAT) and branched chain ketoacid dehydrogenase (BCKD).
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The three branched chain amino acids are unique in that the first catabolic step does not occur in the liver. Leucine, isoleucine, and valine share the first two catabolic enzymes—branched chain aminotransferase (BCAT) and branched chain ketoacid dehydrogenase (BCKD).
openaire +1 more source
GRSF1 Protects Against Heart Failure by Maintaining BCAA Homeostasis
CirculationBACKGROUND: Imbalances in cardiac branched-chain amino acid (BCAA) metabolism and mitochondrial homeostasis are implicated in the onset and development of heart failure.
Chenyu Fan, Jichun Yang, Ling Jin
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