Results 81 to 90 of about 18,005 (233)

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing   +9 more
wiley   +1 more source

The role of BCAA metabolism in metabolic health and disease

open access: yesExperimental & Molecular Medicine
AbstractIt has long been postulated that dietary restriction is beneficial for ensuring longevity and extending the health span of mammals, including humans. In particular, a reduction in protein consumption has been shown to be specifically linked to the beneficial effect of dietary restriction on metabolic disorders, presumably by reducing the ...
Byeong Hun Choi   +2 more
openaire   +3 more sources

Effect of dietary branched chain amino acids on liver related mortality: Results from a large cohort of North American patients with advanced HCV infection

open access: yesPLoS ONE, 2023
Branched chain amino acids (BCAA) supplementation may reduce the incidence of liver failure and hepatocellular carcinoma in patients with cirrhosis. We aimed to determine whether long-term dietary intake of BCAA is associated with liver-related mortality
Lei Yu   +5 more
doaj  

Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

open access: yesNutrition & Metabolism, 2018
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids with protein anabolic properties, which have been studied in a number of muscle wasting disorders for more than 50 years.
Milan Holeček
doaj   +1 more source

Associations between dietary protein sources, plasma BCAA and short-chain acylcarnitine levels in adults

open access: yes, 2019
Elevated plasma branched-chain amino acids (BCAA) and C3 and C5 acylcarnitines (AC) levels observed in individuals with insulin resistance (IR) might be influenced by dietary protein intakes.
Frédéric Guénard   +13 more
core   +1 more source

PENGARUH BCAA DAN AMINO TERHADAP PERUBAHAN KOMPOSISI TUBUH ATLET ROWING JAWA BARAT [PDF]

open access: yes, 2022
Abstrak Protein esensial seperti BCAA dan Amino sangat dibutuhkan bagi atlet yang menjalani latihan daya tahan dan intensitas tinggi. Tujuan pada penelitian ini adalah untuk mengetahui pengaruh BCAA dan Amino terhadap perubahan komposisi tubuh atlet ...
Nilotika Ismawati, -
core  

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

open access: yesCell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo   +5 more
wiley   +1 more source

BCAA upregulates ROS defense system in the liver.

open access: yes, 2013
Copper/zinc Sod (Sod1, Fig. 5-A) and manganese Sod (Sod2, Fig. 5-B) protein levels were increased in the BCAA supplementation group (closed columns, n = 6) compared to the control group (open columns, n = 4).
Yoshiyuki Takei (92839)   +9 more
core   +1 more source

Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang   +6 more
wiley   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

open access: yesThe FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah   +5 more
wiley   +1 more source

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