BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid-derived suppressor cells. [PDF]
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Chen Y, Li H.
europepmc +2 more sources
Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination. [PDF]
: Heparin-binding haemagglutinin (HBHA)-specific immune responses have been linked to protection against tuberculosis (TB). We investigated the hypothesis that BCG vaccination of human infants primes an HBHA-specific response, using multiplex to measure ...
Smith, SG +4 more
core +3 more sources
This article investigates if companies with a stricter control and monitoring system perform better than others in Brazil. The works compares 116 companies in respect to the their independence level between top management team and board directors– being ...
Beatriz Schalka, gilberto sarfati
doaj +1 more source
Secondary Publication: SARS-CoV-2 and Immunological Response
Viruses require the host cellular machinery for protein translation and replication. Upon proliferation, virions damage cells and are released from the infected cells before infecting other cells.
Hidehito Kato, Naoko Yanagisawa
doaj +1 more source
BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi [PDF]
BACKGROUND: BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants.METHODS: Diluted ...
Hazel M. Dockrell +62 more
core +1 more source
BCG vaccination: a role for vitamin D? [PDF]
BCG vaccination is administered in infancy in most countries with the aim of providing protection against tuberculosis. There is increasing interest in the role of vitamin D in immunity to tuberculosis.
Hazel M. Dockrell +35 more
core +1 more source
We report a case of mechanical mitral valve endocarditis associated with miliary disseminated bacillus Calmette-Guerin (BCG) infection following intravesical instillations for minimally invasive bladder cancer in a 65-year-old man.
Francesca Curri +5 more
doaj +1 more source
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R +12 more
core +1 more source
The influence of BCG vaccine strain on mycobacteria-specific and non-specific immune responses in a prospective cohort of infants in Uganda. [PDF]
BACKGROUND: Globally, BCG vaccination varies in efficacy and has some non-specific protective effects. Previous studies comparing BCG strains have been small-scale, with few or no immunological outcomes and have compared TB-specific responses only.
Webb, Emily L +6 more
core +1 more source
Significant elevated CXCL14 and decreased IL-39 levels in patients with tuberculosis
To explore the serum levels of IL-39, CXCL14, and IL-19 in patients with tuberculosis (TB) along with their clinical significances and their concentration changes in macrophages after Bacille Calmette-Guérin vaccine (BCG) or Mycobacterium tuberculosis (M.
Ding Min +7 more
doaj +1 more source

