Results 21 to 30 of about 39,909 (246)

NONMUSCLE INVASIVE TRANSITIONAL CELL CARCINOMA OF URINARY BLADDER – ADJUVANT INTRAVESICAL THERAPIES AFTER TRANSURETHRAL TUMOR RESECTION [PDF]

Romanian Medical Journal, 2017
Introduction. More than 70% of all bladder cancers are nonmuscle invasive involving only the mucosa and the submucosa. A large percentage of patients present local recurrence after endoscopic surgery, and many of them progress to muscle invasive disease ...
Nicolae Grigore, Valentin Pirvut, Ionela Mihai, Adrian Hasegan   +3 more
doaj   +1 more source

Serendipity and strategy in rapid innovation

Nature Communications, 2017
Organizations can take different approaches to innovation: they can either follow a strategic process or a serendipitous perspective. Here Fink et al. develop a statistical model to analyse how components combine to obtain a product and thus explain the ...
T. M. A. Fink, M. Reeves, R. Palma, R. S. Farr   +3 more
doaj   +1 more source

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Paul EM Fine, Sally Stenson, Branson Keith, Rose Blitz, Stenson, Sally, Dockrell Hazel M, Hazel M Dockrell, Floyd Sian, Maeve K Lalor, Rosemary E Weir, Gorak-Stolinska, Patricia, Sian Floyd, Fine, Paul EM, Ben-Smith Anne, Ben-Smith, Anne, Weir Rosemary E, Floyd, Sian, Blitz, Rose, Lalor Maeve K, Weir, Rosemary E, Fine Paul EM, Keith Branson, Anne Ben-Smith, Stenson Sally, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Blitz Rose   +29 more
core   +1 more source

Intravescical instillation of Calmette-Guérin bacillus and COVID-19 risk

Human Vaccines & Immunotherapeutics, 2021
It has been theorized that Calmette-Guérin bacillus may prevent or reduce the severity of COVID-19 through a nonspecific stimulation of the immune system. A preliminary assessment of SARS-CoV-2 infection rates and outcomes among 2803 individuals affected
Ugo Fedeli, Angelo Porreca, Michele Colicchia, Elena Schievano, Walter Artibani, Luigi Roberto Biasio, Giorgio Palù   +6 more
doaj   +1 more source

The effect of birth weight and gestational age on BCG-induced immune responses in infants following BCG vaccination [PDF]

, 2010
Includes bibliographical references (leaves 102-114).Bacillus Calmette?Gu?rin (BCG), the only currently licensed tuberculosis (TB) vaccine, provides variable efficacy. Despite the use of BCG, TB remains a global health problem.
Dube, Frederick
core   +1 more source

A unique case of miliary pulmonary tuberculosis induced by bacillus Calmette-Guérin intravesical instillation with COVID-19 superinfection

South African Journal of Radiology, 2021
Intravesical instillation of Bacillus Calmette-Guérin (BCG) is used as an adjuvant treatment of bladder cancer. Systemic BCG infection occurs in less than 1% of cases, and pulmonary involvement is even rarer (0.3% – 0.7%), with a favourable prognosis.
Nicolò Brandi, Laura Bartalena, Cristina Mosconi, Rita Golfieri   +3 more
doaj   +1 more source

Open Multi-dose Vaccine Vials: Use or Discard? [PDF]

Pediatric Infectious Disease, 2022
Multi-dose vials are useful and economical when large numbers of patients need to be immunized. These multi-dose vials are invaluable in the National Immunization Programme vaccination days, as they save time and effort and also are economically viable ...
Sumitha Nayak
doaj   +1 more source

The staging of re-TURB is crucial in predicting the response to BCG therapy in patients with T1 high-grade bladder cancer [PDF]

Investigative and Clinical Urology
Purpose: This study aimed to evaluate whether the pathological findings from repeat transurethral resection of bladder (re-TURB) predict Bacillus Calmette–Guérin (BCG) response in patients with T1 high-grade bladder cancer.
Hyomyoung Lee, Sang Won So, Jang Hee Han, Hyeong Dong Yuk, Chang Wook Jeong, Ja Hyeon Ku, Cheol Kwak, Seung-hwan Jeong   +7 more
doaj   +1 more source

Anticipated reduction in COVID-19 mortality due to population-wide BCG vaccination: evidence from Germany

Human Vaccines & Immunotherapeutics, 2021
Bacillus Calmette-Guérin (BCG) vaccine is known to have “bystander benefits” in protecting against heterologous infections; interim analysis of the “ACTIVATE” trial shows protection against respiratory infections in the elderly population.
Daniela Marín-Hernández, Douglas F. Nixon, Nathaniel Hupert   +2 more
doaj   +1 more source

Complex cytokine profiles induced by BCG vaccination in UK infants. [PDF]

, 2009
IFNgamma plays an important part in immunity to tuberculosis (TB), but although it is necessary, it is not on its own sufficient for protection against TB.
Fine, Paul E, Fine, Paul E., Hazel M. Dockrell, Dockrell, Hazel M., Floyd, Sian, Weir, Rosemary E., Paul E. Fine, Rose Blitz, Blitz, Rose, Maeve K. Lalor, Lalor, Maeve K., Steven G. Smith, Weir, Rosemary E, Smith, Steven G., Keith Branson, Smith, Steven G, Lalor, Maeve K, Dockrell, Hazel M, Gorak-Stolinska, Patricia, Rosemary E. Weir, Branson, Keith, Patricia Gorak-Stolinska, Sian Floyd   +22 more
core   +1 more source