Results 21 to 30 of about 166,673 (273)

Changes in dendritic complexity and spine morphology following BCG immunization in APP/PS1 mice

Human Vaccines & Immunotherapeutics, 2022
Bacillus Calmette – Guerin (BCG) is an immune regulator that can enhance hippocampal synaptic plasticity in rats; however, it is unclear whether it can improve synaptic function in a mouse model with Alzheimer’s disease (AD).
Qingqing Li, Xiao Wang, Zhao Hua Wang, Zhenzong Lin, Jieyi Yang, Jichun Chen, Rui Wang, Wenfeng Ye, Ya Li, Yingying Wu, Aiguo Xuan   +10 more
doaj   +1 more source

Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]

, 2017
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris, Delanghe, Sigurd, Eloot, Sunny, Glorieux, Griet, Pletinck, Anneleen, Schepers, Eva, Speeckaert, Marijn, Van Biesen, Wim, Van de Velde, Nadeige   +8 more
core   +1 more source

Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency

Virulence, 2020
Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency.
Cecilia B. Korol, Shamira J. Shallom, Kriti Arora, Helena I. Boshoff, Alexandra F. Freeman, Alejandra King, Sonia Agrawal, Sean C. Daugherty, Timothy Jancel, Juraj Kabat, Sundar Ganesan, Marina N. Torrero, Elizabeth P. Sampaio, Clifton Barry, Steve M Holland, Hervé Tettelin, Sergio D Rosenzweig, Adrian M. Zelazny   +17 more
doaj   +1 more source

Cording Mycobacterium tuberculosis Bacilli Have a Key Role in the Progression towards Active Tuberculosis, Which is Stopped by Previous Immune Response

Microorganisms, 2020
Cording was the first virulence factor identified in Mycobacterium tuberculosis (Mtb). We aimed to ascertain its role in the induction of active tuberculosis (TB) in the mouse strain C3HeB/FeJ by testing the immunopathogenic capacity of the H37Rv strain.
Lilibeth Arias, Paula Cardona, Martí Català, Víctor Campo-Pérez, Clara Prats, Cristina Vilaplana, Esther Julián, Pere-Joan Cardona   +7 more
doaj   +1 more source

The impact of HIV exposure and maternal Mycobacterium tuberculosis infection on infant immune responses to bacille Calmette-Guérin vaccination. [PDF]

, 2015
OBJECTIVE: The objective of this study is to assess the effect of maternal HIV and Mycobacterium tuberculosis (Mtb) infection on cellular responses to bacille Calmette-Guérin (BCG) immunization. DESIGN: A mother-infant cohort study.
Adegnika, Borges-Almeida, Brahmbhatt, Chougnet, Clerici, Combadiere, Cotton, Dauby, Economides, Elliott, Elrefaei, Embree, Epalza, Hanekom, Jones, Kampmann, Kemp, Koyanagi, Kuhn, Madhi, Malhotra, Malhotra, Mansoor, Marinda, Mazzola, McNally, Miles, Nakiyingi, Newell, Nielsen, Ono, Otieno, Puissant-Lubrano, Rahman, Resino, Rich, Roederer, Scholzen, Schramm, Schramm, Shapiro, Soares, Torre, Van Rie, Velilla, Weir   +45 more
core   +2 more sources

Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis

Microorganisms, 2020
Mycobacterium bovis (M. bovis) is a zoonotic pathogen that causes bovine and human tuberculosis. Dendritic cells play a critical role in initiating and regulating immune responses by promoting antigen-specific T-cell activation.
Han Liu, Xuekai Xiong, Wenjun Zhai, Tingting Zhu, Xiaojie Zhu, Yifan Zhu, Yongchong Peng, Yongliang Zhang, Jieru Wang, Huanchun Chen, Yingyu Chen, Aizhen Guo   +11 more
doaj   +1 more source

PO and ID BCG vaccination in humans induce distinct mucosal and systemic immune responses and CD4(+) T cell transcriptomal molecular signatures. [PDF]

, 2017
Protective efficacy of Bacillus Calmette-Guérin (BCG) may be affected by the methods and routes of vaccine administration. We have studied the safety and immunogenicity of oral (PO) and/or intradermal (ID) administration of BCG in healthy human subjects.
Andersen, P. L., Blazevic, A., Brusic, V., Dube, T.J., Hill, H., Hoft, D. F., Kaplan, C., Matuschak, G., Schlesinger, L. S., Tennant, J., Xia, M., Zhang, G. L.   +11 more
core   +1 more source

Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine [PDF]

, 2019
Background: Mycobacterium bovis bacillus Calmette-Guerin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e. BCG Danish 1331, Tokyo 172-1 and Russia BCG-1 were
Borgers, Katlyn, Callewaert, Nico, Festjens, Nele, Lin, Yao-Cheng, Michielsen, Gitte, Ou, Jheng-Yang, Plets, Evelyn, Tiels, Petra, Van Hecke, Annelies, Zheng, Po-Xing   +9 more
core   +2 more sources

Effect of Hypertension on Outcomes of High-Risk Patients After BCG-Treated Bladder Cancer [PDF]

, 2015
Immunotherapy with Bacillus Calmette Guerin (BCG) is the most efficacious treatment for high-risk bladder cancer (BC) (Ta/T1 or carcinoma in situ) to reduce the risk of recurrence.
Alberto, Bovo, Alessandro, Crestani, DAL MORO, Fabrizio, Marina P., Gardiman, Roberto, Vettor, Zattoni, Filiberto   +5 more
core   +1 more source

Current and innovative approaches in the treatment of non-muscle invasive bladder cancer: the role of transurethral resection of bladder tumor and organoids

Radiology and Oncology, 2020
Bladder cancer is the 7th most common cancer in men. About 75% of all bladder cancer are non-muscle invasive (NMIBC). The golden standard for definite diagnosis and first-line treatment of NMIBC is transurethral resection of bladder tumour (TURB ...
Taskovska Milena, Kreft Mateja Erdani, Smrkolj Tomaz   +2 more
doaj   +1 more source