Results 61 to 70 of about 39,909 (246)

Apolipoprotein A-I inhibits the increased activities of chitotriosidase and β-glucosaminidase in the liver of mice with BCG-induced tuberculosis inflammation

Сибирский научный медицинский журнал, 2022
The aim of the investigation was to study the activity of lysosomal chitinases (chitotriosidase and β-glucosaminidase) in the liver of mice using a model of BCG-induced tuberculous inflammation after intravenous administration of apolipoprotein A-I ...
L. M. Polyakov, M. V. Kotova, N. V. Trifonova, E. I. Soloveva, R. A. Knyasev   +4 more
doaj   +1 more source

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle [PDF]

, 2006
Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
C. J. Howard, Howard, C J, Hope, J C; id_orcid, P. Sopp, J. C. Hope, Sopp, P   +5 more
core   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Does bacille calmette–Guérin vaccination provides protection against COVID-19: A systematic review and meta-analysis

Indian Journal of Community Medicine, 2021
Background: Lower morbidity and mortality in few geographic locations on the globe suffering with SARS-CoV-2 has been associated with the existing or previously followed long-standing Bacille Calmette–Guérin (BCG) vaccination policy among infants ...
Daisy Khera, Ankita Chugh, Sameer Khasbage, Surjit Singh   +3 more
doaj   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

Phenylacetylcarbinol biotransformation by disrupted yeast cells using ultrasonic treatment in conjunction with a dipropylene glycol mediated biphasic emulsion system

Scientific Reports
Biotransformation of a pharmaceutical precursor, phenylacetylcarbinol (PAC), could be achieved by frozen-thawed Candida tropicalis whole cells (FT-WHC).
Rojarej Nunta, Kritsadaporn Porninta, Sumeth Sommanee, Chatchadaporn Mahakuntha, Charin Techapun, Juan Feng, Su Lwin Htike, Julaluk Khemacheewakul, Yuthana Phimolsiripol, Kittisak Jantanasakulwong, Pornchai Rachtanapun, Usa Bostong, Anbarasu Kumar, Noppol Leksawasdi   +13 more
doaj   +1 more source

Management of Bacille Calmette-Guérin Vaccine Adverse Event: Case Report

Bagcilar Medical Bulletin
Bacillus Calmette-Guérin (BCG) vaccine is used worldwide as an important preventive vaccine against tuberculosis. It is a safe vaccine with a low incidence of serious side effects. However, some adverse events may be observed.
Gizem Kara Elitok
doaj   +1 more source

Proposing BCG Vaccination for Mycobacterium avium ss. paratuberculosis (MAP) Associated Autoimmune Diseases

Microorganisms, 2020
Bacille Calmette−Guerin (BCG) vaccination is widely practiced around the world to protect against the mycobacterial infection tuberculosis. BCG is also effective against the pathogenic mycobacteria that cause leprosy and Buruli’s ulcer.
Coad Thomas Dow
doaj   +1 more source

Polyantigenic Interferon-γ Responses are Associated with Protection from TB Among HIV-Infected Adults with Childhood BCG Immunization. [PDF]

, 2011
Surrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified. HIV-infected adults with childhood BCG immunization entering the placebo arm of the DarDar TB vaccine trial in Dar es Salaam ...
Horsburgh, C Robert, Jenni M. Vuola, Mtei, L., Bakari, M, Pallangyo, K., Mitchell, B.K., Arbeit, R.D., C. Robert Horsburgh, Bakari, Muhammad, Matee, Mecky, C. Fordham von Reyn, Lillian Mtei, Sheth, S., Robert D Arbeit, Arbeit, Robert D, Mtei, Lillian, Mitchell, Brian K, C. Robert Horsburgh5, Muhammad Bakari, MacKenzie, T, Lahey, Timothy, Robert D. Arbeit, Todd MacKenzie, C. Fordham von Reyn1, Matee, M., Sheth, Siddharth, Brian K. Mitchell, Horsburgh, C.R., Vuola, Jenni M, Siddharth Sheth, Mecky Matee, Timothy Lahey, Pallangyo, Kisali, Jenni M Vuola, Kisali Pallangyo, C Fordham von Reyn, von Reyn, C.F., MacKenzie, Todd, Lahey, T., Vuola, J.M., von Reyn, C Fordham, C Robert Horsburgh, Brian K Mitchell   +42 more
core   +2 more sources

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source