Results 81 to 90 of about 57,075 (256)

PROTECTIVE EFFECT INDUCED BY THE NEW SUBUNIT TUBERCULOSIS VACCINE WHEN USED AS A BCG BOOST IS ASSOCIATED WITH INHIBITION OF MYCOBACTERIAL DISSEMINATION

Медицинская иммунология, 2019
Since 1924, BCG vaccine is used to protect children from the most severe forms of tuberculosis. At the same time, the protective effect of BCG in adults is variable. The potential for revaccination with live vaccine is further limited by the rapid spread
V. V. Yeremeev, G. S. Shepelkova, I. V. Dukhovlinov, V. Ya. Gergert   +3 more
doaj   +1 more source

Thai Expectations of the EU's Evolving Security Role: Opportunities and Limitations

Global Policy, EarlyView.
ABSTRACT This article analyses Thailand's perceptions of the European Union (EU) as an actor in the Indo‐Pacific, based on interviews with 13 government officials and foreign policy influencers conducted under the EU in the Indo‐Pacific (EUIP) Jean Monnet Network. It examines how Thai elites interpret the EU's priorities, geopolitical relevance and the
Natthanan Kunnamas, Heidi Maurer
wiley   +1 more source

Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby, Mandana Gholami, Matthew Hong, Michael O'Callaghan   +3 more
wiley   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Immune System Development—Pro Tips for Paediatricians

Acta Paediatrica, EarlyView.
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley   +1 more source

What if Adam Smith Debated an AI Economist: A Thought Experiment on Markets, Ethics, and the Invisible Hand

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Can AI‐driven capitalism sustain the moral preconditions of market order? We stage a dialogue between Adam Smith and a steel‐manned “EconAI” to test four Moral‐Market‐Fitness criteria: trustworthiness, fairness, non‐domination, and contestability, across 11 dilemmas.
Alexandra‐Codruța Bîzoi, Cristian‐Gabriel Bîzoi   +1 more
wiley   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source

Reducing complexity in International Bladder Cancer Group intermediate‐risk non‐muscle‐invasive bladder cancer stratification: a three‐factor approach

BJU International, EarlyView.
Objectives To evaluate whether a simplified risk model preserves the prognostic performance of the International Bladder Cancer Group (IBCG) five‐factor risk stratification model in intermediate‐risk (IR) non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods We performed a multicentre retrospective analysis of 2822 patients with IR NMIBC ...
Jayant Siva, Can Aydogdu, Nicholas Heller, Rishi Jonnalagadda, Patrick J. Hensley, Gabriela M. Diaz, Sean McSweeney, Rebecca Campbell, Nima Almassi, Reza Alaghehbandan, Christopher J. Weight, Ashish M. Kamat, Laura Bukavina   +12 more
wiley   +1 more source

Surveillance patterns in non‐muscle‐invasive bladder cancer across risk groups: a real‐world analysis

BJU International, EarlyView.
Objective To provide insight into real‐world surveillance practices for patients with low‐risk (LR), intermediate‐risk (IR), and (very) high‐risk (HR) non‐muscle invasive bladder cancer (NMIBC). Patients and Methods Cystoscopy surveillance patterns were analysed using real‐world data from two population‐based cohort studies in the Netherlands ...
Lisa M. C. van Hoogstraten, Sita H. Vermeulen, Jasper P. Hof, Antoine G. van der Heijden, Alina Vrieling, Lambertus A. Kiemeney, Katja K. H. Aben   +6 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source