Results 91 to 100 of about 57,303 (248)
Cancer Science, EarlyView.UBE2C upregulates cellular CD147 and enhances its release into the tumor microenvironment both as soluble CD147 (sCD147) and packaged within tumor‐derived exosomes. These CD147‐bearing signals induce T‐cell exhaustion, marked by elevated CTLA‐4 expression and reduced secretion of effector cytokines (IFN‐γ, TNF‐α, TGF‐β), ultimately diminishing CD8+ T ...
Xuwei Hong +7 more
wiley +1 more source
Cancer Science, EarlyView.Ketogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Yuan Zeng +6 more
wiley +1 more source
Evaluating Encodings for Bivariate Edges in Adjacency Matrices
Computer Graphics Forum, EarlyView.Abstract We present the first empirical evaluation of techniques for encoding distributions of quantitative edge values within adjacency matrices. In many real‐world networks, edges represent not a single value but a set of measurements. While adjacency matrices preserve structural clarity, their compact cells limit the simultaneous display of multiple
J. Acosta‐Hernández, A. Lex, T. He
wiley +1 more source
Gender, Work &Organization, EarlyView.ABSTRACT Over the last decade, policy actors have produced a surge of “future of work” reports that reimagine workers through the dual logics of digitalization and human capital. Drawing on 25 policy documents (WEF, World Bank, OECD, EU, and major consultancies) and combining Bacchi and Goodwin's WPR approach with decolonial feminist theory, this paper
Muneeb Ul Lateef Banday
wiley +1 more source
Mixing It Up: Inflation at Risk
Journal of Money, Credit and Banking, EarlyView.Abstract Understanding how risk factors shape the economic outlook is essential for guiding policy decisions. This paper develops a flexible framework that decomposes distributional risk forecasts of macro‐economic variables into underlying contributions and supports the construction of interpretable risk measures.
MAXIMILIAN SCHRÖDER
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Journal of Product Innovation Management, EarlyView.ABSTRACT Academic Summary By integrating artificial intelligence (AI) platforms into their processes, firms aim to enhance their strategic capabilities and gain a competitive advantage. This study investigates the impact of such platforms on value generation within solution‐based strategies, proposing two connected mechanisms.
Yancy Vaillant +2 more
wiley +1 more source
Organizing Buyer‐Side Scope 3 Governance: Sensemaking in Supply Network Decarbonization
Journal of Supply Chain Management, EarlyView.ABSTRACT For many large manufacturers and consumer brands, most greenhouse gas emissions arise outside their own operations and within supplier networks they do not fully control. However, regulators and investors increasingly expect firms to show credible progress on reducing these emissions.
Kim Sundtoft Hald
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Potassium isotopic compositions and exposure ages of evolved and silica‐rich achondrites
Meteoritics &Planetary Science, EarlyView.Abstract Some of the oldest igneous rocks in the Solar System include evolved and silica‐rich achondrites that originate from parent bodies less than 1000 km in diameter, referred to as planetesimals. While Earth was initially in a molten state and required continental crust formation and plate tectonics to generate andesite bulk compositions, evolved ...
Z. Vaci +9 more
wiley +1 more source
Maternal &Child Nutrition, EarlyView.ABSTRACT This study aimed to assess the coverage of essential nutrition interventions delivered through the health system and explored the relationship between co‐coverage and child‐ and maternal‐level factors, household‐level factors, and access to healthcare facilities.
Alemnesh Petros +15 more
wiley +1 more source