Results 101 to 110 of about 96,936 (279)

PROTECTIVE EFFECT INDUCED BY THE NEW SUBUNIT TUBERCULOSIS VACCINE WHEN USED AS A BCG BOOST IS ASSOCIATED WITH INHIBITION OF MYCOBACTERIAL DISSEMINATION

open access: yesМедицинская иммунология, 2019
Since 1924, BCG vaccine is used to protect children from the most severe forms of tuberculosis. At the same time, the protective effect of BCG in adults is variable. The potential for revaccination with live vaccine is further limited by the rapid spread
V. V. Yeremeev   +3 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

BCG-associated AEs from literature meta-analysis.

open access: yes, 2016
BCG-associated AEs from literature meta-analysis.
Christopher Codd (3224925)   +3 more
core   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat   +4 more
wiley   +1 more source

Ag85B-BCG-CWS induces DC maturation.

open access: yes, 2019
(A) DCs were dose-dependently treated with the indicated concentrations of MPL or BCG-CWS for 24 h. TNF-α, IL-6, IL-1β, IL12p70, and IL-10 levels in the culture medium were measured by an ELISA.
Seunga Choi (3202356)   +6 more
core   +1 more source

Value creation and capture in artificial intelligence‐enabled ecosystems

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary We develop an ecosystem perspective on AI‐enabled value creation, grounded in AI's characteristics as a general‐purpose technology. We consider that AI can support multiple value propositions realized through distinct but interconnected ecosystems.
Rahul Kapoor, Manav Raj
wiley   +1 more source

BCG vaccine [PDF]

open access: yes
"BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated. BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease ...

core   +2 more sources

BCG-induced whole blood and intracellular cytokines.

open access: yes, 2018
Blood drawn from 10-week old infants was stimulated ex-vivo with BCG. For whole-blood secreted cytokines, (A, C, E, G), IL-2 and IFN- γ supernatant levels were measured by enzyme-linked immunosorbent assay.
Munyaradzi Musvosvi (4900909)   +13 more
core   +1 more source

Artificial intelligence in out‐of‐hospital sleep monitoring: Bridging polysomnography and wearable signals

open access: yesSleep Research, EarlyView.
Abstract Polysomnography (PSG), the reference standard for sleep assessment, has limited scalability for large‐scale screening, driving the development of wearable and unobtrusive monitors. However, the physiological signals these devices capture are physiologically correlated with PSG channels but are not completely equivalent.
Jing Yan   +5 more
wiley   +1 more source

The response of human dendritic cells to recombinant adenovirus, recombinant Mycobacterium bovis Bacillus Calmette Guerin and biolistic methods of antigen delivery: different induction of contact-dependant and soluble signals.

open access: yes, 2001
Dendritic cells (DCs) are the most potent antigen presenting cells for inducing T-cell immune responses. The ability to grow human DCs from monocyte precursors provides an abundant source of these cells, which can be modified in vitro to present antigens.
Smith, SG   +7 more
core   +1 more source

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