Results 101 to 110 of about 57,515 (295)

Acute Plasmodium yoelii 17XNL Infection During BCG Vaccination Limits T Cell Responses and Mycobacterial Growth Inhibition

open access: yesImmunology, Volume 176, Issue 3, Page 373-384, November 2025.
Tuberculosis and malaria overlap in many sub‐Saharan African countries where BCG vaccination is routinely administered. The aim of this study was to determine whether the timing of BCG vaccination in relation to a malaria infection has implications for BCG vaccine efficacy.
Emily Tangie   +7 more
wiley   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong   +16 more
wiley   +1 more source

In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
In this review, the basic concepts of in situ vaccination are discussed, its advantages over conventional vaccines, and key historical milestones, from the first use of Coley's toxins to the most recent FDA‐approved in situ vaccine for bladder cancer.
Yiru Shi   +4 more
wiley   +1 more source

Leprosy and tuberculosis concomitant infection: a poorly understood, age-old relationship [PDF]

open access: yes, 2014
Historically, archaeological evidence, post-mortem findings and retro- spective analysis of leprosy institutions’ data demonstrates a high observed incidence of concomitant infection with leprosy and tuberculosis (TB).
Anjum, V   +7 more
core  

Immunization Coverage in Migrant School Children Along the Thailand-Myanmar Border [PDF]

open access: yes, 2015
The objective of this project was to document and increase vaccine coverage in migrant school children on the Thailand-Myanmar border. Migrant school children (n = 12,277) were enrolled in a school-based immunization program in four Thai border
Aiko Kaji   +8 more
core   +2 more sources

Identity and stability assessment of BCG vaccine by multiplex PCR

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Multiplex polymerase chain reaction method was used to assess the stability of 7 seed lots of a substrain Mycobacterium bovis BCG-1, Russia, used for the manufacture of BCG vaccine since 1948 till present.
D. T. Levi   +7 more
doaj  

High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis [version 2; referees: 2 approved]

open access: yesF1000Research, 2018
Background: The only available tuberculosis (TB) vaccine, Bacillus Calmette-Guérin (BCG), has variable efficacy. New vaccines are therefore urgently needed.
Andrea Zelmer   +7 more
doaj   +1 more source

Real‐world use of maintenance bacillus Calmette‐Guérin therapy in patients with non‐muscle‐invasive bladder cancer in Japan: ASUKA study

open access: yesBJUI Compass, Volume 6, Issue 10, October 2025.
Abstract Objectives To investigate the real‐world clinical use of maintenance bacillus Calmette‐Guérin (mBCG) therapy for high‐risk non‐muscle‐invasive bladder cancer (HR‐NMIBC) in Japan. Patients and methods This multicentre, retrospective, observational study included patients who received intravesical mBCG for HR‐NMIBC following transurethral ...
Makito Miyake   +6 more
wiley   +1 more source

The Rising Stellar Velocity Dispersion of M87 from Integrated Starlight [PDF]

open access: yes, 2014
We have measured the line-of-sight velocity distribution from integrated stellar light at two points in the outer halo of M87 (NGC 4486), the second-rank galaxy in the Virgo Cluster.
Cradit, Mason   +2 more
core   +2 more sources

Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan   +9 more
wiley   +1 more source

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