Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting? [PDF]
Tuberculosis vaccine candidates are entering clinical studies in areas where BCG fails. This is a high-risk strategy. We suggest that geographical variation in the efficacy of BCG is related to the presence in developing countries of a cross-reactive ...
Dheda, K, Rook, GAW, Zumla, A
core +1 more source
Identity and stability assessment of BCG vaccine by multiplex PCR
Multiplex polymerase chain reaction method was used to assess the stability of 7 seed lots of a substrain Mycobacterium bovis BCG-1, Russia, used for the manufacture of BCG vaccine since 1948 till present.
D. T. Levi +7 more
doaj
Background: The only available tuberculosis (TB) vaccine, Bacillus Calmette-Guérin (BCG), has variable efficacy. New vaccines are therefore urgently needed.
Andrea Zelmer +7 more
doaj +1 more source
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti [PDF]
Alexander S. Pym +4 more
openalex +1 more source
The need for fast-track, high-quality and low-cost studies about the role of the BCG vaccine in the fight against COVID-19 [PDF]
Marcos Pereira +13 more
openalex +1 more source
EPIDEMIOLOGY OF TUBERCULOSIS IN INTERNATIONALLY DISPLACED CHILDREN RESETTLING IN HARRIS COUNTY [PDF]
Background More than 300,000 refugees arrived in the United States (U.S.) from 2010-2015, and Texas accepts the 2nd highest number of refugees. Texas also accepts large numbers of asylees, parolees, and special immigrant visa holders.
LAMB, GABRIELLA S
core +1 more source
Immunization Coverage in Migrant School Children Along the Thailand-Myanmar Border [PDF]
The objective of this project was to document and increase vaccine coverage in migrant school children on the Thailand-Myanmar border. Migrant school children (n = 12,277) were enrolled in a school-based immunization program in four Thai border
Aiko Kaji +8 more
core +2 more sources
Adults are the leading population affected by tuberculosis (TB) epidemic and death. Developing an effective vaccine against adult TB is urgently needed.
Yaqi Wu +6 more
doaj +1 more source
Description of Complete Basic Immunization Coverage Among Infant [PDF]
Immunization coverage in every city/regency must be conducted in accordance with the standard coverage to suppress infectious diseases that can be prevented by vaccination.
Agushybana, F. (Farid) +4 more
core
Training the Fetal Immune System Through Maternal Inflammation-A Layered Hygiene Hypothesis. [PDF]
Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune
Apostol, April C +2 more
core

