Results 91 to 100 of about 723,552 (238)

Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur

BMC Microbiology, 2011
Background Bacille Calmette-Guerin (BCG) is currently the only available vaccine against tuberculosis (TB) and comprises a heterogeneous family of sub-strains with genotypic and phenotypic differences. The World Health Organization (WHO) affirms that the
Degrave Wim M, Castello-Branco Luiz RR, da Silva Renata F, Pereira Melissa P, Gomes Leonardo HF, Correa Paloma R, Kalume Dario E, Berrêdo-Pinho Marcia, Mendonça-Lima Leila   +8 more
doaj   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

MedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge, Dong Han, Jing Wang, Xinyu Dai, Chen Ma, Feihong Chen   +5 more
wiley   +1 more source

The whole genome sequence of Polish vaccine strain Mycobacterium bovis BCG Moreau

Microbiology Spectrum
Currently, tuberculosis immunoprophylaxis is based solely on Bacillus Calmette-Guérin (BCG) vaccination, and some of the new potential tuberculosis vaccines are based on the BCG genome. Therefore, it is reasonable to analyze the genomes of individual BCG
Katarzyna Krysztopa-Grzybowska, Jakub Lach, Maciej Polak, Dominik Strapagiel, Jaroslaw Dziadek, Marcin Olszewski, Aleksandra A. Zasada, Aniela Darlińska, Anna Lutyńska, Ewa Augustynowicz-Kopeć   +9 more
doaj   +1 more source

BCG Vaccination and Tuberculosis in Japan.

Journal of Epidemiology, 2003
This paper summarizes Bacillus Calmette-Guerin (BCG) vaccination and revaccination policies in Japan, its cost-effectiveness, side effects, proposed selective vaccination strategy, and present tuberculosis situation in Japanese perspectives based on Medline database and other published reports.
Rahman, Mahbubur, Takahashi, Osamu, Goto, Masashi, Fukui, Tsuguya   +3 more
openaire   +3 more sources

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Vaccination Drives Alveolar Macrophages Pool Remodeling via Training Resident Cells and Recruiting Monocyte‐Derived Cells to Defend Against Multidrug‐Resistant Acinetobacter baumannii

MedComm, Volume 7, Issue 8, August 2026.
Under homeostatic conditions, the lungs primarily harbor tissue‐resident alveolar macrophages (TR‐AMs). Intranasal immunization with A. baumannii IWC remodels the alveolar macrophage pool via two complementary mechanisms: recruitment and progressive differentiation of CD11B+CD13+ monocyte‐derived AMs, together with direct functional and epigenetic ...
Xiaomin Zhang, Yangyang Zhou, Chuanying Xiang, Ning Wang, Yan Li, Kai Chen, Yu Xie, Hong Yang, Xiangcheng Sun, Yun Shi   +9 more
wiley   +1 more source

Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine

Clinical and Vaccine Immunology, 2016
Our goal is to develop a pediatric combination vaccine to protect the vulnerable infant population against human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) infections.
Kara L. Jensen, M. D. Dela Pena-Ponce, M. Piatak, R. Shoemaker, K. Oswald, W. Jacobs, G. Fennelly, Carissa M. Lucero, K. Mollan, M. Hudgens, A. Amedee, P. Kozlowski, J. Estes, J. Lifson, K. V. Van Rompay, M. Larsen, Kristina De Paris   +16 more
semanticscholar   +1 more source

Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy

Small Science, Volume 6, Issue 8, August 2026.
Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik, Urooj Yousaf Virk, Mohamed Salah Attia, Jenny Wilson, Ming Wei   +4 more
wiley   +1 more source

Manipulation of BCG vaccine: a double-edged sword

European Journal of Clinical Microbiology and Infectious Diseases, 2016
Mycobacterium bovis Bacillus Calmette–Guérin (BCG), an attenuated vaccine derived from M. bovis, is the only licensed vaccine against tuberculosis (TB). Despite its protection against TB in children, the protective efficacy in pulmonary TB is variable in
V. Singh, R. Srivastava, B. S. Srivastava   +2 more
semanticscholar   +1 more source

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf, Abdul Malik, Md Shah Alam, Lijie Li, Haftay Abraha Tadesse, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Htin Lin Aung, Shuai Wang, Tianyu Zhang   +10 more
wiley   +1 more source