Results 91 to 100 of about 34,105 (239)

The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guérin vaccination in southern England and northern Malawi.

, 2006
We report a large study of the effect of BCG vaccination on the in vitro 6-day whole blood interferon-gamma (IFN-gamma) response to antigens from eight species of mycobacteria among schoolchildren in south-eastern England, where bacille Calmette-Guérin ...
Crampin, A.C., Nazareth, B., Stenson, S, Branson, K, Floyd, S., Weir, RE, Branson, K., Fine, P.E.M., Sichali, L., Chaguluka, SD, Chaguluka, S.D., Donovan, L., Weir, R.E., Stanley, C., Donovan, L, Black, G.F., Nazareth, B, Stenson, S., Dockrell, H.M., Sichali, L, Crampin, AC, Dockrell, HM, Black, GF, Stanley, C, Fine, PEM, Floyd, S   +25 more
core   +1 more source

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response. [PDF]

, 2014
BACKGROUND: Tuberculosis (TB) remains a global health problem, with vaccination likely to be a necessary part of a successful control strategy. Results of the first Phase 2b efficacy trial of a candidate vaccine, MVA85A, evaluated in BCG-vaccinated ...
O’Shea, Matthew K., O'Shea, Matthew K, Tameris, Michelle, Willem A Hanekom, Mahomed, Hassan, Fletcher, Helen A, Tanner, R, Matsumiya, Magali, Satti, Iman, Fletcher, HA, Stockdale, L, Thomas J Scriba, Mahomed, H, Hassan Mahomed, Matthew K O’Shea, Scriba, Thomas J, Hanekom, Willem A., Matsumiya, M, Magali Matsumiya, Stockdale, Lisa, Mark Hatherill, Helen McShane, Iman Satti, Tameris, M, Hanekom, Willem A, Harris, Stephanie A., Fletcher, Helen A., Rachel Tanner, Michelle Tameris, Hatherill, M, Hanekom, WA, Scriba, Thomas J., Stephanie A Harris, Harris, Stephanie A, Tanner, Rachel, Lisa Stockdale, Scriba, TJ, O’Shea, Matthew K, Hatherill, Mark, Helen A Fletcher, Satti, I, Harris, SA, McShane, H, O'Shea, MK, McShane, Helen   +44 more
core   +1 more source

A Protocol of National Mixed‐Methods Assessment of Childhood and Maternal Immunization

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Accurate measurement of routine immunization coverage is essential for detecting immunity gaps, guiding programmatic responses, and supporting equitable vaccine delivery. Iran's Expanded Programme on Immunization has achieved high coverage, but administrative estimates can mask some disparities.
Seyed Aria Nejadghaderi, Paria Dehesh, Mehran Nakhaeizadeh, Mohammadreza Rajabalipour, Faeze Tahrudi, Naser Nasiri, Seyed Mohsen Zahraei, Hamid Sharifi, AliAkbar Haghdoost   +8 more
wiley   +1 more source

The influence of BCG on vaccine responses – a systematic review

Expert Review of Vaccines, 2018
Introduction: Bacillus Calmette-Guérin (BCG) vaccine is one of the most widely used vaccines worldwide. In addition to providing protection against tuberculosis, it has non-specific (heterologous) immunomodulatory effects.
Petra Zimmermann, Nigel Curtis
doaj   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

Still Standing Strong: A Narrative Review of Why BCG Remains Central to Global Tuberculosis Control

Scripta Score Scientific Medical Journal
Background: Tuberculosis is one of the deadliest infectious diseases in the world. However, the BCG vaccine has shown significant results and remains in use to this day. Objective: This review aims to provide a comprehensive perspective on the resilience
Ardaniel Euprasia Simarmata, Paul Behring Manurung, Andre Marolop Pangihutan Siahaan   +2 more
doaj   +1 more source

Intravesical Delivery of P21 mRNA–Loaded Lipid Nanoparticles as a Tumor Suppressor Replacement Therapy for Bladder Cancer

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Intravesical delivery of p21 mRNA‐loaded lipid nanoparticles (p21‐LNP) restores the tumor suppressor p21 in bladder cancer. Localized p21 expression directly induces cell cycle arrest, DNA damage and apoptosis, and ultimately inhibits orthotopic tumor growth with minimal systemic distribution and favorable safety.
Jie Zeng, Ziyi Cao, Chenghe Wang, Yingjie Xu   +3 more
wiley   +1 more source

The response of human dendritic cells to recombinant adenovirus, recombinant Mycobacterium bovis Bacillus Calmette Guerin and biolistic methods of antigen delivery: different induction of contact-dependant and soluble signals.

, 2001
Dendritic cells (DCs) are the most potent antigen presenting cells for inducing T-cell immune responses. The ability to grow human DCs from monocyte precursors provides an abundant source of these cells, which can be modified in vitro to present antigens.
Smith, SG, Patel, PM, Steven G Smith, Peter J Selby, Jackson, AM, Poulam M Patel, Andrew M Jackson, Selby, PJ   +7 more
core   +1 more source

Bacillus Calmette-Guérin vaccine related lymphadenitis in children: Management guidelines endorsed by the Saudi Pediatric Infectious Diseases Society (SPIDS)

International Journal of Pediatrics & Adolescent Medicine, 2015
The Bacillus Calmette-Guérin (BCG) vaccine contains live attenuated Mycobacte-rium bovis; was first used in humans to prevent tuberculosis (TB) in 1921.
Nagi Elsidig, Dayel Alshahrani, Mohammed Alshehri, Mohammed Alzahrani, Sami Alhajjar, Suliman Aljummah, Ibrahim Bin Hussain, Mohammad Alshaalan, Fahad Alzamil, Abdularahman Alodyani, Fahad Aljobair   +10 more
doaj   +1 more source

Robust-gamma delta(+) T cell expansion in infants immunized at birth with BCG vaccine

, 2007
Cell-mediated immune responses to BCG vaccine were evaluated in 7-month-old infants vaccinated with intradermal combined BCG and Hepatitis B or intradermal BCG and intramuscular Hepatitis B at birth.
T.N. Mazzola, Da Silva, M. T. N., I. Raw, E.F. Carniel, Raw, I., Y.M.F. Moreno, M.A.R.G.M. Antonio, A. Aranha Netto, Carniel, E. F., M.H. Blotta, Lima, S. C. B. S., Mazzola, T. N., Antonio, M. A. R. G. M., Blotta, Maria Heloisa de Souza Lima [UNIFESP], Morcillo, A. M., M.L. Zanolli, S.C.B.S. Lima, M.M.S. Vilela, Moreno, Y. M. F., Zanolli, M. L., A.M. Morcillo, Netto, A. Aranha, Vilela, M. M. S., M.T.N. Da Silva   +23 more
core   +1 more source