Results 101 to 110 of about 389,087 (235)
The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.Abstract Sasanlimab is a monoclonal antibody (mAb) which blocks human programed cell death protein 1. It is administered subcutaneously (SC), currently under development for non‐muscle invasive bladder cancer (NMIBC) with a recommended flat dose of 300 mg every 4 weeks (Q4W).
Joanna C. Masters +8 more
wiley +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
MedComm, Volume 7, Issue 9, September 2026.This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle [PDF]
, 2006 Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
C. J. Howard +5 more
core +1 more source
Abscopal Effect in Radiation Therapy: The Immune Mechanisms and Clinical Advances
MedComm, Volume 7, Issue 9, September 2026.The schematic outlines the key events of the abscopal effect. (Ignition) Local radiotherapy (RT) induces the release of immunogenic signals from the tumor, leading to dendritic cell (DC) activation. (Orchestration) In the tumor‐draining lymph node (TDLN), DCs prime naive T cells into cytotoxic T lymphocytes (CTLs), a process modulated by regulatory T ...
Yihong Dong +5 more
wiley +1 more source
The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice [PDF]
, 2006 The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice Rahajeng N. Tunjung*, Dwi Pudjonarko** Background.
Tunjung, Rahajeng_N.
core +1 more source
npj VaccinesDevelopment of a new vaccine for tuberculosis (TB) to replace the BCG vaccine has been hampered by the lack of a preclinical vaccine model that accurately reflects the genetic heterogeneity of the human population. We previously tested both Collaborative
Rocky Lai +9 more
doaj +1 more source
Public Health Challenges, Volume 5, Issue 3, September 2026.ABSTRACT Pediatric tuberculosis remains a neglected health emergency, particularly in fragile contexts such as North Kivu province in the Democratic Republic of Congo. While more than one million children contract tuberculosis each year worldwide, the majority of cases remain underdiagnosed, resulting in preventable morbidity and mortality.
Germain Cebweru Murhola +6 more
wiley +1 more source
Public Health Challenges, Volume 5, Issue 3, September 2026.ABSTRACT Under‐5 child mortality due to vaccine preventable diseases (VPDs) contributes to an estimated burden of ∼5.2 million deaths globally, mostly within low‐ and middle‐income countries (LMICs). Despite ongoing efforts to expand immunisation coverage, gaps in immunisation remain a persistent public health concern, underscoring the need to examine ...
Mansi Malik +3 more
wiley +1 more source
, 2006 We report a large study of the effect of BCG vaccination on the in vitro 6-day whole blood interferon-gamma (IFN-gamma) response to antigens from eight species of mycobacteria among schoolchildren in south-eastern England, where bacille Calmette-Guérin ...
Crampin, A.C. +25 more
core +1 more source
Public Health Challenges, Volume 5, Issue 3, September 2026.Latent tuberculosis infection is common among adults living with HIV in Kinshasa. Advanced immunosuppression, previous TB exposure, and contact with active TB cases were independently associated with LTBI, supporting systematic screening and targeted tuberculosis preventive therapy.
José Mutambayi Kadima +10 more
wiley +1 more source