Results 101 to 110 of about 34,105 (239)

Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer [PDF]

open access: yes, 2016
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M.
Miriam Bolz   +26 more
core   +1 more source

Identity and stability assessment of BCG vaccine by multiplex PCR

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Multiplex polymerase chain reaction method was used to assess the stability of 7 seed lots of a substrain Mycobacterium bovis BCG-1, Russia, used for the manufacture of BCG vaccine since 1948 till present.
D. T. Levi   +7 more
doaj  

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

Evaluation of a reverse tetracycline inducible system in recombinant BCG to improve stability and immunogenicity

open access: yes, 2011
The aim of this study is to utilise the tetracycline dependent gene regulation system to down-regulate recombinant antigen expression in BCG during the expansion of seed stocks and up-regulate expression prior to or post ...
Mbele, Prisca
core  

The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice [PDF]

open access: yes, 2006
The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice Rahajeng N. Tunjung*, Dwi Pudjonarko** Background.
Tunjung, Rahajeng_N.
core  

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle

open access: yes, 2006
Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
C. J. Howard   +5 more
core   +1 more source

Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom. [PDF]

open access: yes, 2004
To investigate the role of innate immunity in variable efficacy of Mycobacterium bovis BCG vaccination in Malawi and the United Kingdom, we examined 24-h tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses to mycobacterial ...
Elizabeth King   +41 more
core   +1 more source

Association between BCG-induced immunity and risk of TB disease

open access: yes, 2011
We tested the hypothesis that a lower frequency and profile of specific T cells induced by BCG vaccination at birth is associated with subsequent risk of developing ...
Kagina, Benjamin Mugo
core  

Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial. [PDF]

open access: yes, 2014
BACKGROUND: Novel tuberculosis vaccines should be safe, immunogenic, and effective in various population groups, including HIV-infected individuals. In this phase II multi-centre, double-blind, placebo-controlled trial, the safety and immunogenicity of ...
Said, Khadija   +67 more
core   +1 more source

The influence of prior exposure to environmental mycobacteria on the IFN-(gamma) response to BCG vaccination in southern England and northern Malaw

open access: yes, 2006
We report a large study of the effect of BCG vaccination on the in vitro 6-day whole blood interferon-gamma (IFN-γ) response to antigens from eight species of mycobacteria among schoolchildren in south-eastern England, where bacille Calmette–Guérin (
Donovan, L   +12 more
core  

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