Results 101 to 110 of about 723,552 (238)

Still Standing Strong: A Narrative Review of Why BCG Remains Central to Global Tuberculosis Control

Scripta Score Scientific Medical Journal
Background: Tuberculosis is one of the deadliest infectious diseases in the world. However, the BCG vaccine has shown significant results and remains in use to this day. Objective: This review aims to provide a comprehensive perspective on the resilience
Ardaniel Euprasia Simarmata, Paul Behring Manurung, Andre Marolop Pangihutan Siahaan   +2 more
doaj   +1 more source

Bacillus Calmette-Guérin vaccine related lymphadenitis in children: Management guidelines endorsed by the Saudi Pediatric Infectious Diseases Society (SPIDS)

International Journal of Pediatrics & Adolescent Medicine, 2015
The Bacillus Calmette-Guérin (BCG) vaccine contains live attenuated Mycobacte-rium bovis; was first used in humans to prevent tuberculosis (TB) in 1921.
Nagi Elsidig, Dayel Alshahrani, Mohammed Alshehri, Mohammed Alzahrani, Sami Alhajjar, Suliman Aljummah, Ibrahim Bin Hussain, Mohammad Alshaalan, Fahad Alzamil, Abdularahman Alodyani, Fahad Aljobair   +10 more
doaj   +1 more source

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

Cell Proliferation, Volume 59, Issue 8, August 2026.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song, Yujie Jiang, Yu Zhang, Danyi Ao, Chunjun Ye, Xiya Huang, Yingqiong Zhou, Hanle Yang, Ruolan Xia, Jiayuan Ai, Dandan Wan, Aiping Tong, Yuquan Wei, Xuemei He, Aqu Alu, Xiawei Wei   +15 more
wiley   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1012-1027, August 2026.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Identity and stability assessment of BCG vaccine by multiplex PCR

Биопрепараты: Профилактика, диагностика, лечение, 2018
Multiplex polymerase chain reaction method was used to assess the stability of 7 seed lots of a substrain Mycobacterium bovis BCG-1, Russia, used for the manufacture of BCG vaccine since 1948 till present.
D. T. Levi, Yu. I. Obukhov, N. V. Aleksandrova, R. A. Volkova, E. V. Elbert, M. V. Alvarez Figeroa, A. V. Prokopenko, R. I. Ludanniy   +7 more
doaj  

High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis [version 2; referees: 2 approved]

F1000Research, 2018
Background: The only available tuberculosis (TB) vaccine, Bacillus Calmette-Guérin (BCG), has variable efficacy. New vaccines are therefore urgently needed.
Andrea Zelmer, Lisa Stockdale, Satria A. Prabowo, Felipe Cia, Natasha Spink, Matthew Gibb, Ayad Eddaoudi, Helen A. Fletcher   +7 more
doaj   +1 more source

The Efficacy of the BCG Vaccine against Newly Emerging Clinical Strains of Mycobacterium tuberculosis

PLoS ONE, 2015
To date, most new vaccines against Mycobacterium tuberculosis, including new recombinant versions of the current BCG vaccine, have usually been screened against the laboratory strains H37Rv or Erdman. In this study we took advantage of our recent work in
Marcela Henao-Tamayo, Crystal A. Shanley, D. Verma, Andrew Zilavy, Margaret C. Stapleton, S. Furney, Brendan K. Podell, I. Orme   +7 more
semanticscholar   +1 more source

[BCG vaccination in the world].

Kekkaku : [Tuberculosis], 2000
BCG vaccination programme and BCG vaccination coverage in the world were summarized mainly based on the published informations from official organizations, such as World Health Organization (WHO), International Union Against Tuberculosis and Lung Disease (IUATLD) and Centers for Disease Control and Prevention (CDC).
openaire   +2 more sources

Molecular analysis of Mycobacterium isolates from patients with BCG-induced lymphadenitis

International Journal of Mycobacteriology, 2015
The Bacillus Calmette-Guérin (BCG) vaccine is administered to all newborns within the first days of life for the prevention of tuberculosis (TB) in many of the developing countries, including Iran.
Farahnoosh Doustdar, Fatemeh Shahi, Fatemeh Fallah, Hossein Goudarzi, Maryam Baniasad, Bahman Pourabbas   +5 more
doaj  

Evaluation of combined BCG and SARS-CoV-2 vaccination for immune enhancement and lung protection in Syrian hamsters

Scientific Reports
SARS-CoV-2 (SCV2) has posed significant global challenges, necessitating improved immunization strategies to enhance protection and mitigate disease severity.
Abbas Ashtari, Bahar Nayeri Fasaei, Morteza Taghizadeh, Seyed Mehdi Joghataei, Mehran Dabaghian, Nader Mosavari, Mohammad Eslampanah, Ayyoob Arpanaei   +7 more
doaj   +1 more source