Results 61 to 70 of about 223,551 (298)
Effect of cinnamaldehyde on Bax/Bak and apoptosis of vascular endothelial cells in diabetic ulcers
Objective To investigate the effects of cinnamic aldehyde (CA) on Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak) in vascular endothelial cells of diabetic ulcer wound tissues, as well as on cell apoptosis.
JIN Zheyu, XIE Chenlei , FAN Xinqi
doaj +1 more source
FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing [PDF]
FOXP3 promotes the development and function of regulatory T cells mainly through regulating the transcription of target genes. RNA alternative splicing has been implicated in a wide range of physiological and pathophysiological processes.
Du, Jianguang +3 more
core +1 more source
Protective Effects of Baicalin on Experimental Myocardial Infarction in Rats
Objective: This study aimed to investigate the protective effects of baicalin on myocardial infarction in rats and explore the related mechanisms. Methods: Fifty Sprague Dawley rats were randomly divided into the control, model, and low-, medium- and ...
Longfei Wang +5 more
doaj +1 more source
Curcumin: a bioactive compound with molecular targets for human malignancies
Cancer is the second leading cause of death in the world and one of the major public health problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting proliferation and invasion of tumours by suppressing a variety of cellular ...
Muhammad Shahbaz +12 more
doaj +1 more source
Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. [PDF]
BackgroundIn multiple sclerosis (MS) and its widely used animal model, experimental autoimmune encephalomyelitis (EAE), autoreactive T cells contribute importantly to central nervous system (CNS) tissue damage and disease progression. Promoting apoptosis
Chen, Yingyu +3 more
core +2 more sources
Protein nutrition is particularly important for the self-renewal processes of gastrointestinal epithelial cells. The self-renewal of cells is inseparable from the interaction between apoptosis and autophagy.
Zhiwei Kong +3 more
doaj +1 more source
Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano +3 more
core +2 more sources
Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. [PDF]
The aim of this study was to determine whether heat-shock pretreatment exerted a protective effect against sorbitol-induced apoptotic cell death in K562, U937 and HeLa cell lines and whether such protection was associated with a decreased cytochrome c
Aventaggiato, Michele +8 more
core +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Cytotoxic effects of curcumin on osteosarcoma cell lines [PDF]
Summary: Curcumin (diferuloylmethane), one of the main components of the Indian spice turmeric, is known to possess potent anti-inflammatory and anti-oxidant properties.
Born, Walter +4 more
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