Results 71 to 80 of about 36,627,339 (183)

1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells

open access: yesMolecules, 2019
1-O-Hexyl-2,3,5-trimethylhydroquinone (HTHQ) has previously been found to have effective anti-oxidant and anti-lipid-peroxidative activity. We aimed to elucidate whether HTHQ can prevent dopaminergic neuronal cell death by investigating the effect on l ...
Hyun Jin Park   +2 more
doaj   +1 more source

Combined effects of 17β-estradiol and exercise training on cardiac apoptosis in ovariectomized rats.

open access: yesPLoS ONE, 2018
BACKGROUND:The purpose of this study was to investigate the combined 17β-estradiol (E2) and exercise training on cardiac pro-survival and anti-apoptotic pathways in ovariectomized rats.
Yi-Yuan Lin   +9 more
doaj   +1 more source

Critical Roles of VEGFR1, VEGFR2, VEGFR3, BAX, and BCL-2 in the Pathogenesis of Varicose Veins: Unveiling Molecular Mechanisms

open access: yesAmerican Journal of Men's Health
Varicocele is characterized by the abnormal dilation of veins within the testicular pampiniform plexus, contributing to inflammation, pain, and infertility in males.
Mehdi Abedinzadeh   +4 more
doaj   +1 more source

Impact of platelet-rich plasma at different concentrations on genes of apoptotic pathway and differentiation of stem cells in cyclophosphamide-induced ovarian failure in a mouse model: An experimental study

open access: yesInternational Journal of Reproductive BioMedicine
Background: Platelet-rich plasma (PRP), a new therapeutic technique, has the potential to regenerate failing ovarian tissue and alleviate symptoms in patients with premature ovarian failure (POF).
Gholamreza Fotoohi-Ardakani   +4 more
doaj   +1 more source

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

open access: yes, 2022
BCL-2 family proteins regulate the mitochondrial apoptotic pathway. BOK a multidomain BCL-2 family protein is generally believed to be an adaptor protein similar to BAK and BAX regulating the mitochondrial permeability transition during apoptosis.
Fiona Brown (1432693)   +24 more
core   +1 more source

The role of the notch signalling pathway in vascular smooth muscle cell apoptosis [PDF]

open access: yes, 2004
The Notch signalling system is a highly conserved method of cell-to-cell communication involved in cell fate decisions in many cell types. Until recently, the importance of the Notch signalling pathway was recognized in the embryonic but not in the adult
Sweeney, Catherine Helena
core   +2 more sources

Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways

open access: yesJournal of International Medical Research, 2019
Objective The objective was to further investigate apoptosis induction by Babao Dan (BBD), which supports its anti-tumor mechanisms, using two human gastric cancer cell lines (AGS and MGC80-3).
Haixia Shang   +9 more
doaj   +1 more source

Bcl-2, tissue transglutaminase and p53 protein expression in the apoptotic cascade in ribs of premature infants

open access: yes, 2000
Apoptotic cells of the human growth plate have not previously been demonstrated in situ. We have investigated the distribution of apoptotic cells in costosternal growth plates and bone of premature infants aged 4–11 d with a gestational age of ∼ 26 wk ...
Stevens, H.Y., Noble, B.S., Reeve, J.
core   +1 more source

Regulation of Mitochondria-dependent Apoptosis in Non-Small Cell Lung Cancer: Implications for Cancer Therapy [PDF]

open access: yes, 2007
Summary The work described in this thesis focuses on the characterization of the mechanism(s) underlying the deregulated activation of the intrinsic or mitochondrial apoptotic pathway in non-small cell lung cancer (NSCLC) cells.
Checinska, A.
core  

Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells [PDF]

open access: yes, 2012
Background: Alzheimer’s disease (AD) involves increased accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles as well as neuronal loss in various regions of the neocortex.
Anderson, G.   +14 more
core   +2 more sources

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