Results 1 to 10 of about 34,325,732 (253)
Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer. [PDF]
Anticancer Res, 2017 Bcl-2-like protein 11 (BIM) is a pro-apoptotic member of the Bcl-2 protein family. BIM elicits cell death by binding to pro-survival Bcl-2 proteins. Even though the association of BIM expression with cell death has been investigated, its clinical survival significance in cervical cancer has not.
Kim BW +6 more
europepmc +5 more sources
Exp Ther Med, 2020 Numerous reports have shown that dysfunction of vascular smooth muscle cells (VSMCs) serves a critical function in the development of cardiovascular disease, including coronary heart disease (CHD). microRNAs (miRNAs/miRs) have been reported to play important roles in regulating the function of VSMCs. The present study aimed to determine the role of miR-
Zhang H, Xue S, Feng Y, Shen J, Zhao J.
europepmc +4 more sources
[Retracted] MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11. [PDF]
Exp Ther Med[This retracts the article DOI: 10.3892/etm.2020.8517.].
Zhang H, Xue S, Feng Y, Shen J, Zhao J.
europepmc +3 more sources
PRDX1 Influences The Occurrence and Progression of Liver Cancer by Inhibiting Mitochondrial Apoptosis Pathway [PDF]
Cell Journal, 2022 ObjectiveThe aim of this study is to elucidate the role of PRDX1 in hepatocellular carcinoma using hepatomacells.Materials and MethodsIn this experimental study, we elucidated role of PRDX1, using hepatoma cell lines.ResultsPRDX1 was upregulated in ...
Hong-hua Sun +4 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Extracellular vesicles (EVs) are a popular treatment candidate for myocardial injury. This work investigated the effects of mesenchymal stem cells (MSCs)–secreted EVs–derived miR‐200b‐3p on cardiomyocyte apoptosis and inflammatory response ...
Jun Wan +6 more
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Archives of Medical Science, 2022 Introduction In this study, we aimed to investigate the role of rs531564 and the underlying signaling pathways. Material and methods Five hundred and twenty-eight spinal cord injury (SCI) patients were genotyped for the analysis of the effect of ...
Zhuang Zhang, Rubo Sui, Dongjian Xia
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Bcl-2-Like Protein 11 Deletion Polymorphism Predicts Survival in Advanced Non–Small-Cell Lung Cancer [PDF]
Journal of Thoracic Oncology, 2014 Germline Bcl-2-like protein 11 (BIM) deletion polymorphism in Asian is a poor predictive factor for treatment outcomes to tyrosine kinase inhibitors (TKIs) in malignancies. We explored the impact of BIM deletion polymorphism on treatment outcome of advanced non-small-cell lung cancer (NSCLC).We prospectively collected tissue samples, blood, and ...
Lee, Jih-Hsiang +12 more
openaire +2 more sources
Long Non-Coding RNA PNKY Modulates the Development of Choroidal Neovascularization
Frontiers in Cell and Developmental Biology, 2022 Long non-coding RNAs (lncRNAs) have been widely implicated in human diseases. Our aim was to explore the regulatory role of changes in the expression levels of PNKY and its linked signaling networks in mediating stress-induced choroidal ...
Lianjun Shi +14 more
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Electrotaxis of alveolar epithelial cells in direct-current electric fields
Chinese Journal of Traumatology, 2023 Purpose: This study aims to elucidate the electrotaxis response of alveolar epithelial cells (AECs) in direct-current electric fields (EFs), explore the impact of EFs on the cell fate of AECs, and lay the foundation for future exploitation of EFs for the
Chao-Yue Yang +11 more
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Journal of Translational Medicine, 2023 Background Irinotecan (CPT-11) is a classic chemotherapeutic agent that plays an important role in the clinical treatment of metastatic colon cancer and other malignant tumors. We previously designed a series of novel irinotecan derivatives.
Yongqi Li +9 more
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