Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells [PDF]
Apoptosis 16:619-26 (2011), 2011 Apoptosis is a complex pathway regulated by the concerted action of multiple pro- and anti-apoptotic molecules. The intrinsic (mitochondrial) pathway of apoptosis is governed up-stream of mitochondria, by the family of Bcl-2 proteins, and down-stream of mitochondria, by low-probability events, such as apoptosome formation, and by feedback circuits ...
arxiv
Nano-honeycomb electrode based QCM sensor and its application for PPI detection [PDF]
, 2019 An anodic aluminon oxide (AAO)-based nano honeycomb electrode was coated on a quartz crystal for use as a sensing device in a quartz crystal microbalance (QCM) to monitor the protein-protein interactions (PPIs).
Asai Naoto +12 more
core +2 more sources
Advanced Science, EarlyView.Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang +14 more
wiley +1 more source
Analysis of a Mathematical Model of Apoptosis: Individual Differences and Malfunction in Programmed Cell Death [PDF]
arXiv, 2010 Apoptosis is an important area of research because of its role in keeping a mature multicellular organism's number of cells constant hence, ensuring that the organism does not have cell accumulation that may transform into cancer with additional hallmarks.
arxiv
Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis [PDF]
, 2006 Apoptosis has been recognized as a central component in the pathogenesis of atherosclerosis, in addition to the other human pathologies such as cancer and diabetes.
A Ashkenazi +142 more
core +1 more source
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
Advanced Science, EarlyView.This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng +8 more
wiley +1 more source
Cell Cycling Models of Carcinogenesis: A Complex Systems Analysis [PDF]
arXiv, 2004 A new approach to the modular, complex systems analysis of nonlinear dynamics in cell cycling network transformations involved in carcinogenesis is proposed. Carcinogenesis is a complex process that involves dynamically inter-connected biomolecules in the intercellular, membrane, cytosolic, nuclear and nucleolar compartments that form numerous inter ...
arxiv
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Familija Bcl 2 proteina kod malignih bolesti [PDF]
Vojnosanitetski Pregled, 2004 Brajušković Goran R. +6 more
doaj +1 more source
Ginger extract (Zingiber officinale Roscoe) triggers apoptosis in hepatocarcinogenesis induced rats [PDF]
, 2008 Ginger extract has been reported previously by our group to exhibit anticancer and an-tioxidant effects by reducing tumour burden and lipid peroxidation respectively in he-patocarcinogenesis induced rats.
Harlianshah H, +7 more
core