Results 101 to 110 of about 247,080 (161)

Crossing ocular barriers with quercetin-SPIONs: modulation of Bax/Bcl-2 balance in normal rat eyes. [PDF]

BMC Pharmacol Toxicol
Hajiaghajanian M, Movahedi N, Pouriaii D, Souri Z, Rezayat A, Esmaeili A.   +5 more
europepmc   +1 more source

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines. [PDF]

Mol Med Rep
Ren L, Li Z, Dai C, Zhao D, Wang Y, Ma C, Liu C.   +6 more
europepmc   +1 more source

Streptomyces koyangensis L-asparaginase: computational prediction of dual-mechanism BCL-2 interaction in acute lymphoblastic leukemia. [PDF]

Sci Rep
Solanki G, Prajapati C, Gadhvi R, Kamble L, Sharma MC, Hajare ST.   +5 more
europepmc   +1 more source

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia. [PDF]

Blood Neoplasia
Ung J, Tan SF, Shaw JJP, Taori M, Deddens TM, Venancio G, Montgomery MM, Hagen JT, Aruleba RT, Golla UR, Sharma A, Paudel BB, Lee I, Ramamoorthy B, Janes KA, Garrett-Bakelman F, Cabot MC, Fisher-Wellman KH, Fox TE, Claxton DF, Chalfant CE, Feith DJ, Loughran TP.   +22 more
europepmc   +1 more source

Mechanistic overview and suggested strategies to overcome BCL-2 inhibitor resistance in <i>TP53-</i>mutated acute myeloid leukemia. [PDF]

Front Cell Dev Biol
Iqbal U, Shallis RM.
europepmc   +1 more source

In vitro bioactivity, cytotoxicity, and gene silencing of graphene oxide as a Bcl-2 siRNA carrier in osteosarcoma cells with in vivo inflammatory response. [PDF]

Sci Rep
Saravanabhavan SS, Sarang Z, Marimuthu N, Raju SVV, Nissapatorn V, Sergi CM.   +5 more
europepmc   +1 more source

Retraction: Vitamin C and Turmeric Attenuate Bax and Bcl-2 Proteins' Expressions and DNA Damage in Lead Acetate-Induced Liver Injury. [PDF]

Dose Response
europepmc   +1 more source

Minocycline Is Cytoprotective in Human Trabecular Meshwork Cells and Optic Nerve Head Astrocytes by Increasing Expression of XIAP, Survivin, and Bcl-2 [Retraction]. [PDF]

Clin Ophthalmol
europepmc   +1 more source

BCL-2 family proteins form distinct functional interaction networks when primed with full-length BAD compared with the BAD-like mimetic ABT-737

Gilmore A, Pedley R, Mellor C, King L, Nelson L, Tennant F, Jones M, Taylor-Hearn I, Lawless C, Mironov A.   +9 more
europepmc   +1 more source

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Targeting the Bcl-2

Current Opinion in Oncology, 2009
Members of the Bcl-2 family of proteins are critical components in regulating the intrinsic apoptotic pathway. Bcl-2 protein overexpression is associated with drug resistance and poor clinical outcome in cancer patients. Preclinical and clinical evaluations demonstrate that downregulation of Bcl-2 restores the intrinsic apoptotic pathways with ...
Mehul P, Patel, Aisha, Masood, Priya S, Patel, Asher A, Chanan-Khan   +3 more
openaire   +2 more sources