Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai +8 more
wiley +1 more source
Investigating mushroom LMW compounds as potential Bcl-2 inhibitors: docking studies using AutoDock4 [PDF]
, 2016 The B cell CLL/lymphoma-2 (Bcl-2) family is functionally classified as either anti-apoptotic or pro-apoptotic, and the regulation of its interactions dictates survival or commitment to apoptosis.
Abreu, Rui M.V. +3 more
core
Transient mitotic phase localization of bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis. [PDF]
, 1994 Mark C. Willingham, Kapil N. Bhalla
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Animal Models and Experimental Medicine, EarlyView.Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang +7 more
wiley +1 more source
Alterations of the p53 tumor suppressor gene in diffuse large cell lymphomas with translocations of the c-MYC and BCL-2 proto-oncogenes [PDF]
, 1994 M. Michéle Farrugia +4 more
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A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment
Animal Models and Experimental Medicine, EarlyView.A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng +4 more
wiley +1 more source
Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis [PDF]
, 2003 We have shown here that the apoptosis inducer staurosporine causes an early decrease in the endogenous respiration rate in intact 143B.TK- cells. On the other hand, the activity of cytochrome c oxidase is unchanged for the first 8 h after staurosporine ...
Attardi, Giuseppe +5 more
core
H‐2Z Homozygous New Zealand Mice as a Model for B‐Cell Chronic Lymphocytic Leukemia: Elevated bcl‐2 Expression in CD5 B Cells at Premalignant and Malignant Stages [PDF]
, 1993 Hiroshi Okamoto +5 more
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Advanced NanoBiomed Research, EarlyView.Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli +3 more
wiley +1 more source