Results 201 to 210 of about 408,548 (333)

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

Clinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas   +8 more
wiley   +1 more source

Reprogramming the Apoptosis-Autophagy Axis in Glioblastoma: The Central Role of the Bcl-2:Beclin-1 Complex and Survival Signalling Networks. [PDF]

Cells
Christoff M, Szczepańska A, Jakubowicz-Gil J, Zając A.   +3 more
europepmc   +1 more source

Estrogen Modulates Bcl-2 Family Proteins in Ischemic Brain Injury

, 2006
Chung‐Kil Won, Myeong Ok Kim, Phil‐Ok Koh   +2 more
openalex   +2 more sources

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

BCL-2 Family Inhibition Enhances mTORC1/2 Inhibition in PIK3CA-Mutant Colorectal Cancer. [PDF]

Mol Cancer Ther
DeStefanis RA, Schmitz AE, Steimle AK, Payne SN, Sha GC, Olson AM, Cornelio A, Lippert AEL, Kraus SG, Johnson KA, Favreau PF, Gillette A, Babiarz C, Miller D, Sprackling CM, Pasch CA, Pritzl S, Van De Hey DR, Korkos DP, Foley TM, Yueh AE, Greane ALJX, Clipson L, Skala MC, Deming DA.   +24 more
europepmc   +1 more source

Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI‐1) Deficient Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang, Juandi Liu, Jing Jin, Deng Pan, Lei Shao   +4 more
wiley   +1 more source

Bcl-2 and FAS as Apoptosis-Related Markers in Patients with Convulsive Status Epilepticus. [PDF]

J Clin Med
Ćorić L, Sović S, Šimac B, Mihaljević I, Vukasović I, Čolak Romić Z, Šušak Sporiš I, Petelin Gadže Ž.   +7 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

BCL-2 family dysregulation in HTLV-1 and BLV pathogenesis and its implications for leukemogenesis and therapy. [PDF]

Mol Biol Rep
Akbarin MM, Farjami Z, Acevedo-Jiménez GE, Murillo CR, González-Fernández VD, de María Avila-De la Vega L, Martínez MA, Santos HJN, Álvarez HR.   +8 more
europepmc   +1 more source

The ZIKA Virus Delays Cell Death through the Anti-Apoptotic Bcl-2 Family Proteins

, 2019
Jonathan Turpin, Étienne Frumence, Philippe Desprès, Wildriss Viranaïcken, Pascale Krejbich‐Trotot   +4 more
openalex   +2 more sources