Results 241 to 250 of about 408,548 (333)

Cleavage of Bcl-2-associated athanogene by metacaspase determines plant antiviral immunity. [PDF]

Nat Commun
Liang L, Jiang Y, Zhao P, Wang H, Chen X, Lin X, Sun Y, Zhang W, Fang R, Ye J.   +9 more
europepmc   +1 more source

Adverse outcomes among pregnant women with COVID‐19 according to hospitalization status: A prospective individual participant data meta‐analysis in Europe and North America

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Understanding the varied impact of COVID‐19 severity on pregnancy outcomes is crucial for informed clinical management and targeted interventions. Objective To evaluate the impact of COVID‐19 on pregnancy outcomes, distinguishing between pregnant women managed in primary care and those requiring hospitalization.
Odette de Bruin, Emeline Maisonneuve, Eimir Hurley, Hedvig M. E. Nordeng, Anick Bérard, Odile Sheehy, Padma Kaul, Mayura U. Shinde, Austin Cosgrove, Jennifer G. Lyons, Elizabeth Messenger‐Jones, Maria E. Kempner, Sengwee Toh, Wei Hua, José J. Hernández‐Muñoz, Leyla Sahin, Carolyn E. Cesta, David Hägg, Rosa Gini, Olga Paoletti, Beatriz Poblador‐Plou, Sue Jordan, Clara L. Rodríguez‐Bernal, Francisco Sánchez‐Sáez, Régis Lassalle, Marie‐Agnès Bernard, Fariba Ahmadizar, Guillaume Favre, Alice Panchaud, Kitty W. M. Bloemenkamp, Kelly Plueschke, Corinne de Vries, Satu J. Siiskonen, Miriam C. J. M. Sturkenboom, on behalf of the CONSIGN Collaboration Group, Benjamin P. Geisler, Mark Walker, Steven Hawken, Sasha Bernatsky, Sherif Eltonsy, Emma Hoffman, Andrew B. Petrone, Jolene Mosley, Jenice Ko, Claudia Bartolini, Giuseppe Roberto, Giorgio Limoncella, Anna Girardi, Giulia Hyeraci, Antonio Gimeno‐Miguel, Jonás Carmona‐Pírez, Antonio Poncel‐Falcó, Aida Moreno‐Juste, Alexandra Prados‐Torres, Daniel Thayer, Ian Farr, Saira Ahmed, Ieuan Scanlon, Gabriel Sanfélix‐Gimeno, Isabel Hurtado, Anibal Garcia‐Sempere, Salvador Peiro, Jérémy Jové, Dunia Sakr, Cécile Droz‐Perroteau, Ema Alsina, David Baud, Hilde M. Engjom, Judit Riera‐Arnau, Mònica Sabaté Gallego, Elena Ballarín Alins, Cristina Aguilera Martin, Melissa Kampman, Celline Brasil   +73 more
wiley   +1 more source

Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans. [PDF]

Biomolecules
Chen CC, Hsia CW, Huang WC, Chang CC, Darmanto AG, Sheu JR.   +5 more
europepmc   +1 more source

Porodica proteina BCL-2

, 2010
Kako bi se održala homeostaza broja stanica u nekom organizmu, milijarde stanica dnevno umiru uslijed procesa apoptoze. Egzekutorsko djelovanje u ovom procesu vrše cisteinske proteaze kaspaze potaknute različitim stresnim signalima. No, u procesu apoptoze bitnu ulogu imaju i proteini iz porodice BCL-2.
openaire   +1 more source

Intrapartum oral azithromycin for maternal infection prophylaxis and the risk of postpartum hemorrhage: A secondary analysis of the A‐PLUS trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective A single oral dose of azithromycin (AZM) given during labor to women planning a vaginal delivery reduced maternal infections including sepsis, with a stronger effect in sub‐Saharan Africa than South Asia. Since maternal infection contributes to labor dysfunction and postpartum hemorrhage (PPH), we evaluated the effect of AZM on the ...
Larissa Sidze, Janet L. Moore, Waldemar A. Carlo, Musaku Mwenechanya, Elwyn Chomba, Jennifer J. Hemingway‐Foday, Avinash Kavi, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Richard Derman, Adrien L. Lokangaka, Antoinette K. Tshefu, Melissa S. Bauserman, Carl L. Bose, Poonam Shivkumar, Manjushri Waikar, Archana B. Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Osayame A. Ekhaguere, Sherri L. Bucher, Saleem Jessani, Shiyam Sunder Tikmani, Sarah Saleem, Robert L. Goldenberg, Sk Masum Billah, Ruth Lennox, Rashidul Haque, William A. Petri, Lester Figueroa, Manolo Mazariegos, Nancy F. Krebs, Tracy L. Nolen, Marion Koso‐Thomas, Elizabeth M. McClure, Alan T. N. Tita, for the A‐PLUS Trial Group   +37 more
wiley   +1 more source

Melatonin Reduces Radiation-induced Apoptosis Through Change of bax and bcl-2 Expression in Peripheral Blood Lymphocytes. [PDF]

Adv Biomed Res
Motallebzadeh E, Talaei SA, Mohseni M.
europepmc   +1 more source

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

The role of Bcl‑2 in controlling the transition between autophagy and apoptosis (Review). [PDF]

Mol Med Rep
Palabiyik AA.
europepmc   +1 more source

The complex regulatory mechanisms of the BCL-2 family of proteins in cancer

, 2019
GJ Greaves
openalex   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source