Results 241 to 250 of about 24,683,651 (289)

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia. [PDF]

open access: yesBlood Neoplasia
Ung J   +22 more
europepmc   +1 more source

BCL-2 family proteins form distinct functional interaction networks when primed with full-length BAD compared with the BAD-like mimetic ABT-737

open access: yes
Gilmore A   +9 more
europepmc   +1 more source

Targeting the Bcl-2

Current Opinion in Oncology, 2009
Members of the Bcl-2 family of proteins are critical components in regulating the intrinsic apoptotic pathway. Bcl-2 protein overexpression is associated with drug resistance and poor clinical outcome in cancer patients. Preclinical and clinical evaluations demonstrate that downregulation of Bcl-2 restores the intrinsic apoptotic pathways with ...
Mehul P, Patel   +3 more
openaire   +2 more sources

BCL-2 FAMILY: Regulators of Cell Death

Annual Review of Immunology, 1998
S J Korsmeyer
exaly  

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