Results 261 to 270 of about 369,993 (297)

Topoisomerase-I inhibitors for human malignant glioma: Differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and β-lapachone

, 1997
Michael Weller, Stephan Winter, Christine R. Schmidt, Peter Esser, A. Fontana, J. Dichgans, Peter Groscurth   +6 more
openalex   +1 more source

Subtype-specific prognostic impact of Bcl-2 in HER2-positive and HER2-negative breast cancer. [PDF]

Sci Rep
Kim T, Lim ST, Choi HS, Cho IJ, Noh H, Lee JI, Han A.   +6 more
europepmc   +1 more source

Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection

, 1998
F Petschner, Christine Zimmermann, Andreas Strasser, Didier Grillot, Gabriel Núñez, Hanspeter Pircher   +5 more
openalex   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Production and characterization of a promising microbial-derived lipase enzyme targeting BCL-2 gene expression in hepatocellular carcinoma. [PDF]

Microb Cell Fact
Abo-Kamer AM, Abdelaziz AA, Elkotb ES, Al-Madboly LA.   +3 more
europepmc   +1 more source

Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers

Ibrain, EarlyView.
This review highlights the potential of gold nanoparticles (AuNPs) in overcoming the blood‐brain barrier (BBB) to improve brain tumor treatment. By enabling targeted drug delivery and enhancing therapies like radiotherapy, phototherapy, and chemotherapy, AuNPs offer a promising approach for safer, more effective treatments of glioblastoma and other ...
Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi   +4 more
wiley   +1 more source

Development of a clinical prediction model for sensitivity to combination therapy of Bcl-2 inhibitors and hypomethylating agents in elderly/unfit patients with acute myeloid leukemia. [PDF]

Discov Oncol
Du Y, Li C, Chen Y, Xie F, Yan J.
europepmc   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

<i>In-silico</i> analysis of nsSNPs in <i>BCL-2</i> family proteins: Implications for colorectal cancer pathogenesis and therapeutics. [PDF]

Biochem Biophys Rep
Kong AS, Tan YC, Thew HY, Lai KS, Lim SE, Maran S, Loh HS.   +6 more
europepmc   +1 more source

Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53

, 1997
I. K. Bukholm, Jahn M. Nesland, Rolf Kåresen, U Jacobsen, Anne‐Lise Børresen‐Dale   +4 more
openalex   +1 more source