Renoprotective Potential of the Ultra-Pure Lipopolysaccharide from Rhodobacter Sphaeroides on Acutely Injured Kidneys in an Animal Model [PDF]
One of the main causes of acute kidney injury is ischemic reperfusion injury (IRI). Inflammatory response, apoptotic damages, and oxidative stress-related injuries are all involved in the pathogenesis of IRI.
Munaf Aal-Aaboda +2 more
doaj +1 more source
Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution [PDF]
Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia.
Meejeong Kim +7 more
doaj +1 more source
Effect of 8 weeks high-intensity interval training (HIIT) with and without caloric restriction on gene expression of myocardial Bax and Bcl2 in mice [PDF]
Background: Apoptosis is the physiological cell death that in natural conditions leads to the elimination of old, damaged, waste, and harmful cells. The aim of this study was the effect of eight weeks of high-intensity interval training (HIIT) with and ...
Mohammadreza Zarali +3 more
doaj +1 more source
Effect of N-acetyl cysteine on oxidative stress and Bax and Bcl2 expression in the kidney tissue of rats exposed to lead [PDF]
This study aimed to consider the lead-induced oxidative damage of the kidney of male rats and the role of antioxidant N-acetylcysteine (NAC) in preserving cells against Pb toxicity.
M. Gholami +4 more
doaj +1 more source
Solitary Fibrous Tumour of the Clavicle: A Rare Case Report [PDF]
A Solitary Fibrous Tumour (SFT) is the preferred term by most of the pathologists than “haemangiopericytoma”. SFT is a heterogeneous group of benign and malignant neoplasms along a morphologic continuum. Here we report a case of SFT of the clavicle in a
Dileep Krishnamoorty Srinivas +4 more
doaj +1 more source
Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an
Yongqiang Chen +6 more
doaj +1 more source
Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
doaj +1 more source
Scutellarein apoptosis mediated by mitochondria in oral squamous cell carcinomas
Background: The growth of several cancers can be inhibited by naturally occurring medicinal plants. A flavone called Scutellarein found in the perennial herb Scutellaria lateriflora does have a wide range of biological functions. Scutellarein was studied
Markandan Birundadevi +2 more
doaj +1 more source
The effect of training on mitochondrial mitophagy factors in obese male rats [PDF]
purpose: Mitophagy can assist in mitochondrial quality control. The aim of this study was to investigate the effect of training on mitochondrial mitophagy factors in obese male rats.Methods: In this experimental study, 40 male rats (weight 120 ± 20 g ...
Mozhgan Ahmadi +1 more
doaj +1 more source
Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas. [PDF]
MYC-driven lymphomas, especially those with concurrent MYC and BCL2 dysregulation, are currently a challenge in clinical practice due to rapid disease progression, resistance to standard chemotherapy, and high risk of refractory disease.
Bi, Chengfeng +15 more
core +1 more source

