Biomedical Papers, 2021 Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
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Green Synthesis of Bismuth Oxide Nanoparticle by cell-free extract of Spirulina Platensis and evaluation of its performance on expression of apoptosis regulator genes in MCF-7 breast cancer cell line [PDF]
Journal of Epigenetics, 2022 Background and Aim: Bismuth and its related compounds such as bismuth oxide nanoparticles (Bi2O3 NPs) are widely used in the medical field of science for drug delivery, cancer therapy, bio imaging, and fighting against pathogenic microorganisms.
Maedeh Khorami +2 more
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Similar clinical features in follicular lymphomas with and without breaks in the BCL2 locus. [PDF]
, 2016 Approximately 15% of follicular lymphomas (FLs) lack breaks in the BCL2 locus. The aim of this study was to better define molecular and clinical features of BCL2-breakpoint/t(14;18)-negative FLs.
Puppe, B +23 more
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BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy [PDF]
, 2015 Disruption of the complex of BECN1 with BCL2 or BCL2L1/BCL-XL is an essential switch that turns on cellular autophagy in response to environmental stress or treatment with BH3 peptidomimetics.
Pedro, Jose Manuel Bravo San +7 more
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Age related neoplasm in experimental animals [PDF]
Iraqi Journal of Veterinary SciencesThe albino rats are commonly recognized as tumor-resistant and appreciable research interest because of the scarcity of reports and article papers on neoplasm tumors.
Hadil B. Al-Sabaawy
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Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome. [PDF]
Adv Sci (Weinh)Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Deng Z +14 more
europepmc +2 more sources
Inverting the BTK-BCL2 order [PDF]
Blood, 2020 In this issue of Blood, Lin et al report the first long-term follow-up data showing that Bruton tyrosine kinase inhibitors (BTKi's) are effective in chronic lymphocytic leukemia (CLL) after previous progression on venetoclax.
openaire +2 more sources
South Asian Journal of Cancer, 2014 Background and Objective: Persistent high risk human papilloma virus (HPV) infection is probably the best predictor of increased risk of cervical cancer, but expression of certain markers of cell proliferation and apoptosis have been studied. The present
Shailaja Shukla +2 more
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BCL2 inhibition: back to the future!
In this issue of Blood, Liu and colleagues report the preliminary characterization of a new BCL2-specific inhibitor (BCL2i), sonrotoclax, which not only binds with higher affinity to BCL2 than the first-in-class BCL2i venetoclax, but also induces ...
Martin JS Dyer (8194578) +1 more
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Methanol leaf extract of Azadirachta indica mitigates isoproterenol-induced myocardial infarction through the modulation of oxidative stress, and PPARα and BCL2 signaling in rats [PDF]
Avicenna Journal of PhytomedicineObjective: Evaluation of Azadirachta indica’s potential on the modulation of blood pressure parameters, antioxidant defense status, as well as immunohistochemical expressions of Peroxisome proliferator-activated receptor α (PPARα) and Bcl-2 (B-cell ...
Amirah Yusuf +11 more
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