Results 21 to 30 of about 91,646 (261)
Solitary Fibrous Tumour of the Clavicle: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 A Solitary Fibrous Tumour (SFT) is the preferred term by most of the pathologists than “haemangiopericytoma”. SFT is a heterogeneous group of benign and malignant neoplasms along a morphologic continuum. Here we report a case of SFT of the clavicle in a
Dileep Krishnamoorty Srinivas +4 more
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Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis [PDF]
Nature Communications, 2020 AbstractViral control of programmed cell death relies in part on the expression of viral analogs of the B-cell lymphoma 2 (Bcl2) protein known as viral Bcl2s (vBcl2s). vBcl2s control apoptosis by interacting with host pro- and anti-apoptotic members of the Bcl2 family.
Maria Jesús García-Murria +6 more
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The Incomplete Puzzle of the BCL2 Proteins [PDF]
Cells, 2019 The proteins of the BCL2 family are key players in multiple cellular processes, chief amongst them being the regulation of mitochondrial integrity and apoptotic cell death. These proteins establish an intricate interaction network that expands both the cytosol and the surface of organelles to dictate the cell fate.
Hector Flores-Romero +1 more
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Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
Autophagy Reports, 2023 Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an
Yongqiang Chen +6 more
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Biomedical Papers, 2021 Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
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Green Synthesis of Bismuth Oxide Nanoparticle by cell-free extract of Spirulina Platensis and evaluation of its performance on expression of apoptosis regulator genes in MCF-7 breast cancer cell line [PDF]
Journal of Epigenetics, 2022 Background and Aim: Bismuth and its related compounds such as bismuth oxide nanoparticles (Bi2O3 NPs) are widely used in the medical field of science for drug delivery, cancer therapy, bio imaging, and fighting against pathogenic microorganisms.
Maedeh Khorami +2 more
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Inverting the BTK-BCL2 order [PDF]
Blood, 2020 In this issue of Blood, Lin et al report the first long-term follow-up data showing that Bruton tyrosine kinase inhibitors (BTKi's) are effective in chronic lymphocytic leukemia (CLL) after previous progression on venetoclax.
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Quantitative Analysis of Tumor-Specific BCL2 Expression in DLBCL: Refinement of Prognostic Relevance of BCL2 [PDF]
Blood, 2019 Introduction Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and a heterogeneous disease with a variety of molecular aberrations and diverse clinical outcomes. BCL2 expression has been implicated for a poor prognosis among patients with DLBCL.
Roh, Jin +16 more
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Age related neoplasm in experimental animals [PDF]
Iraqi Journal of Veterinary SciencesThe albino rats are commonly recognized as tumor-resistant and appreciable research interest because of the scarcity of reports and article papers on neoplasm tumors.
Hadil B. Al-Sabaawy
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South Asian Journal of Cancer, 2014 Background and Objective: Persistent high risk human papilloma virus (HPV) infection is probably the best predictor of increased risk of cervical cancer, but expression of certain markers of cell proliferation and apoptosis have been studied. The present
Shailaja Shukla +2 more
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