Results 1 to 10 of about 9,374 (115)

Additional role of ECC in the detection and treatment of cervical HSIL

Frontiers in Medicine, 2023
ObjectiveTo probe into the additional role of ECC in the detection of cervical HSIL. The primary objective was to risk-stratify HSIL patients according to ECC so as to provide clinical suggestions for subsequent treatment.MethodsRetrospective analysis of
Li Sijing, Jia Ying, Wu Jing, Li Xiaoge, Luo Ming, Duan Zhaoning   +5 more
doaj   +3 more sources

A Clinical Prediction Model for Pathologic Upgrade to Invasive Carcinoma Following Conization of Cervical High‐Grade Squamous Intraepithelial Lesions

Cancer Medicine
Objective To explore the risk factors associated with the pathological progression to invasive carcinoma following the conization of cervical high‐grade squamous intraepithelial lesions (HSIL) and to construct a risk prediction model to guide ...
Qiao Liu, Jing Yang, Hui Cheng, Chuqiang Shu, Yi Tang, Jing Zhao   +5 more
doaj   +2 more sources

Transcriptomic profiling of select genes associated with cervical cancer and its preneoplastic lesions in Nigerian patients: an in vivo and in silico study [PDF]

BMC Cancer
Objective Cervical cancer remains a leading cause of cancer-related mortality among women in Nigeria, primarily due to late detection. Genetic alterations in host genes contribute significantly to its pathogenesis.
Saviour God’swealth Usin, Gershom Akanmu Olajire, Joshua Osekponor Olumese, Emeka Ogwa Idenyi, Olukayode Oluwafemi, Timothy Abiola Oluwasola, Ayodeji A. Salami, Olaposi Idowu Omotuyi, Gabriel O. Ogun, Michael Adedapo Gbadegesin   +9 more
doaj   +2 more sources

The Importance of Ki-67, p16, C-erb-B2, and Cyclin D1 Expressions in LSIL, HSIL, and Cervical Squamous Cell Carcinoma Biopsies

Zeynep Kamil Tıp Bülteni, 2018
Objective: The squamous cell carcinoma (SCC) of the cervix is the most common malignant tumor of gynecological cancers. Squamous intraepithelial lesions (SILs) are known as a preinvasive lesion. Due to problems in the grading of these lesions that are effective in the development of cervical cancer, immunohistochemical markers are reported to be useful
Birgül TOK, Şafak ERSÖZ, Gülname FINDIK GÜVENDİ   +2 more
openaire   +1 more source

Peripheral blood immune cell parameters in patients with high-grade squamous intraepithelial lesion (HSIL) and cervical cancer and their clinical value: a retrospective study [PDF]

PeerJ
Objective The objective of this study was to delineate the profile of peripheral blood lymphocytic indices in patients afflicted with high-grade squamous intraepithelial lesions (HSIL) and cervical neoplasms, and to elucidate the correlation of these ...
Ling Wang, Yuyan Dong
doaj   +2 more sources

Associação entre o polimorfismo no códon 72 da p53 e as lesões pré-malignas e malignas cervicais Association of codon 72 polymorphism with premalignant and malignant cervical lesions

Revista Brasileira de Ginecologia e Obstetrícia, 2005
OBJETIVOS: testar a hipótese de que o polimorfismo no códon 72 do gene TP53 é fator de risco para as lesões pré-malignas e malignas cervicais associadas ou não ao papilomavírus humano (HPV).
Fernando Anschau, Virgínia Minghelli Schmitt, Manoel Afonso Guimarães Gonçalves, Bernardo Garicochea   +3 more
doaj   +1 more source

Evaluation of the category high-grade squamous intraepithelial lesion in The Bethesda System for reporting cervical cytology

Journal of Cytology, 2013
Background: High grade squamous intraepithelial lesion (HSIL) is a category of The Bethesda System (TBS) for reporting cervical cytology that is in vogue since the introduction of the said system in 1988 and it was not modified in 2001 modification of ...
Subhalakshmi Mukhopadhyay, Sumit Ray, Supria Dhar, Ranjana Bandyopadhyay, Swapan K Sinha   +4 more
doaj   +1 more source

Early effect of bivalent human papillomavirus vaccination on cytology outcomes in cervical samples among young women in the Netherlands

Cancer Medicine, 2023
Background The first HPV‐vaccine eligible cohorts in the Netherlands will enter the cervical screening program in 2023. However, a substantial number of young women already have had a cervical sample taken before entry into the regular screening program.
Tessa M. Schurink‐van ’t Klooster, Albert G. Siebers, Joske Hoes, Folkert J. vanKemenade, Johannes Berkhof, Johannes A. Bogaards, Hester E. deMelker   +6 more
doaj   +1 more source

IMMUNOHISTOCHEMICAL EXPRESSION OF P53, BCL2 AND CD34 IN CERVICAL INTRAEPITHELIAL NEOPLASIAS AND CARCINOMAS

The Iraqi Journal of Medical Sciences, 2016
Background:Cervical cancer is the fourth most common cancer affecting women worldwide. Immunohistochemical expression of several biomarkers; including those regulating apoptosis and angiogenesis; may help to distinguish reactive conditions from ...
Mohammed K. Chaloob, Alaa G. Hussein, Ban J. Qasim   +2 more
doaj   +6 more sources

The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women

BMC Cancer, 2018
Background To explore the diagnostic value of FAM19A4 methylation in high-risk human papilloma virus (hrHPV)-positive cervical samples from Chinese women for estimating cervical cancer or its precancerous lesions.
Qiaowen Bu, Sanfeng Wang, Jian Ma, Xiangcheng Zhou, Guiying Hu, Hua Deng, Xiaoli Sun, Xiaoshan Hong, Hengying Wu, Liang Zhang, Xiping Luo   +10 more
doaj   +1 more source