Results 211 to 220 of about 91,646 (261)

Therapeutic Potential of Carica papaya (L.) Extract on NRF2/KEAP1 and Apoptotic Pathways in Asbestos‐Induced Lung Toxicity

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Asbestos exposure induced oxidative stress, apoptosis, and lung tissue damage in animal models. Treatment with Carica papaya (500 mg/kg) extract improved antioxidant status, reduced oxidative stress biomarkers, and restored lung architecture. Gene expression analysis showed modulation of NRF2/KEAP1 and apoptotic pathways.
Usman Haider, Muhammad Ahmad, Wania Nasir, Najeeb Ullah Khan, Muhammad Saad Tariq, Bilal Aslam, Saif Ur Rehman, Junming Sun   +7 more
wiley   +1 more source

Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs. [PDF]

Ren Fail
Pei S, Li D, Yu X, Huang X, Liu J, Song Y, Zhu L, Cui J, Cui Y, Xie K.   +9 more
europepmc   +1 more source

Unraveling the Bioactive Compounds and Multi‐Target Mechanisms of the Fructus Aurantii Immaturus‐Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma, Weiwei Xie, Jing Song, Yabin Qin, Yile Zhao   +4 more
wiley   +1 more source

<i>Lavandula stoechas</i> Ethanol Extracts Induce Apoptosis in Breast, Bladder, and Glioblastoma Cancer Cells. [PDF]

Pharmaceutics
Nalkiran I, Sevim Nalkiran H.
europepmc   +1 more source

A Network Toxicology Framework for Identification of Immune System Disruption by Per- and Polyfluoroalkyl Substance (PFAS) Mixture: In Silico Analysis. [PDF]

J Xenobiot
Baralić K, Vidić K, Marić Đ, Živanović J, Buha Djordjevic A, Ćurčić M, Bulat Z, Antonijević B, Đukić-Ćosić D.   +8 more
europepmc   +1 more source

Autophagy hub genes mediate photodynamic therapy tolerance in nasopharyngeal carcinoma through cytoprotective autophagy and survival signaling. [PDF]

J Mol Histol
Peng Y, Wen D, Bing Y, Di C, Jian K.
europepmc   +1 more source

Recurrent Genomic Alterations in BCRi‐Experienced CLL Patients Treated With Venetoclax: Extended Phase 2 Follow‐Up

American Journal of Hematology, Volume 101, Issue 7, Page 1516-1521, July 2026.
Jennifer A. Woyach, Relja Popovic, Emily L. Rossi, Sanjana Singh, Toshihiko Oki, Tanya S. Rosenberg, Chen Qian, Michael Moran, Zihuan Liu, Michelle Boyer, Jeffrey Jones, Richard R. Furman, William Wierda, Jason Gotlib, Stephen J. Schuster, Brenda Chyla, Matthew S. Davids   +16 more
wiley   +1 more source

Integrated transcriptomic, protein, and MicroRNA profiling reveals a conserved pyroptosis-related molecular signature across breast cancer subtypes. [PDF]

Front Mol Biosci
Panfil A, Sirek T, Sirek A, Zmarzły N, Wróbel M, Wróbel Z, Boroń K, Boroń D, Ossowski P, Stefaniak M, Ordon P, Wyrobiec G, Wyrobiec P, Grabarek BO.   +13 more
europepmc   +1 more source

Clearance of Senescent Cells by BCL_XL-PROTAC: A Novel Approach to Treat COPD? [PDF]

Aging Cell
Devulder JV, Fenwick PS, Kolosionek E, Al-Sahaf M, Viola P, Lemaire R, Razdan N, Kudo H, Sinadinos A, Odqvist L, Donnelly LE, Barnes PJ.   +11 more
europepmc   +1 more source