Alantolactone Inhibits Double Expression Lymphoma via Dual-Targeted Glycogen Synthase Kinase 3 Beta and B-Cell Lymphoma2. [PDF]
Blood Lymphat CancerChen J +10 more
europepmc +1 more source
Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression
The FEBS Journal, EarlyView.T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera +5 more
wiley +1 more source
Combinatorial BCL2/BCL2L1 expression predicts clinical response to ruxolitinib in myelofibrosis. [PDF]
Biomark ResColtro G +6 more
europepmc +1 more source
306 | CENTRAL NERVOUS SYSTEM RELAPSE IN HIGH‐GRADE B‐CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS: A MULTICENTER STUDY FROM THE SPANISH GROUP GELTAMO [PDF]
Cristina García Herce +37 more
openalex +1 more source
Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis
The FEBS Journal, EarlyView.The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe +7 more
wiley +1 more source
Racial Differences in the Molecular Genetic Biomarkers of Diffuse Large B-Cell Lymphoma. [PDF]
BiomedicinesGomes MD +7 more
europepmc +1 more source
BCL2-associated X protein (BAX); BCL2-antagonist/killer 1 (BAK1; BAK); B cell lymphoma 2 (BCL-2; BCL2); BCL2 homology domain 3 (BH3) [PDF]
Science-Business eXchange, 2013 openaire +1 more source