Results 241 to 250 of about 108,551 (297)

Mouse models of B cell lymphomas on the basis of genetic features. [PDF]

Front Immunol
Yuan M, Wang JQ.
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Long-Term Impact of Early-Life Stress on Hippocampal Apoptotic Gene Expression in BALB/c Mice. [PDF]

Neurochem Res
Barokah AN, Gürsoy İK, Dönmez MH, Fitremann J, Bayram A, Bayram KK.   +5 more
europepmc   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With Microdosing. [PDF]

CPT Pharmacometrics Syst Pharmacol
Burlot C, Riglet F, Romagnoli M, Leconte A, Delmas A, Schmitt A, Fouliard S.   +6 more
europepmc   +1 more source

Mitochondrial dynamics and repair differences in two mouse models of Friedreich's ataxia

The Journal of Physiology, EarlyView.
Abstract figure legend Differential mitochondrial remodelling in Friedreich's ataxia (FA)‐associated cardiomyopathy. Schematic summary of mitochondrial alterations in two mouse models of FA exhibiting distinct cardiac phenotypes. In cardiac/skeletal muscle‐specific MCK‐Cre frataxin knockout (FXN‐cKO) mice, which develop heart failure with reduced ...
Lili Salinas, Francisco Figueroa, Claire B. Montgomery‐Bowie, Garrett P. Cox, Gino Cortopassi, Elena N. Dedkova   +5 more
wiley   +1 more source

High Histological Skeletonization as a Measure of Heterogeneity Is Associated with Poor Overall Survival and Death Within 2 Years of Diffuse Large B-Cell Lymphoma. [PDF]

Cancers (Basel)
Carreras J, Kikuti YY, Nagase S, Roncador G, Ikoma H, Ito A, Orita M, Tomita S, Tanigaki Y, Ueno A, Kondo Y, Nakamura N, Masugi Y.   +12 more
europepmc   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Epstein-Barr Virus DNA Detection Without Detectable Expression of Selected Viral Transcripts in Pediatric Patients with Systemic Lupus Erythematosus. [PDF]

Genes (Basel)
Galliano I, Rotondaro A, Massobrio A, Clemente A, Cito A, Calvi C, Gambarino S, Licciardi F, Bergallo M.   +8 more
europepmc   +1 more source