Results 251 to 260 of about 108,551 (297)

The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System

Glia, Volume 74, Issue 11, November 2026.
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada, Hinako Saito, Riko Takahashi, Mio Fujisato, Yukina Hosoda, Binri Sasaki, Momona Yamada, Sakurako Abe, Chikako Hayashi, Akira Yoshimoto, Ryunosuke Ohkawa, Tomal Julian Matt, Florence M Bareyre, Stefan Berghoff, Mikael Simons, Nobuharu Suzuki   +15 more
wiley   +1 more source

Genomic Subtype Influences BH3 Mimetic Drug Sensitivity and Synergy with Cytotoxic Chemotherapeutics in T-cell Acute Lymphoblastic Leukemia. [PDF]

Clin Cancer Res
Yoshimura S, Li Y, Inoue S, Meyer CT, Yang X, Du G, Hsiao YC, Li Z, Yang W, Hu J, Andersen CL, Saygin C, Karol SE, Bernt KM, Yu J, Stock W, Teachey DT, Konopleva M, Yang JJ.   +18 more
europepmc   +1 more source

Cytotoxic, Drug-Interaction, and Apoptosis-Associated Effects of β-Boswellic Acid and Doxorubicin in Murine 4T1 TNBC-like Cells. [PDF]

Biomedicines
Küçük Z, Tuncer MC, Öztürk Ş.
europepmc   +1 more source

MiR-376c-3p Targets STRBP mRNA to Regulate Cashmere Goat Hair Follicle Stem Cell Proliferation and Multipotency by Inhibiting the Wnt/β-Catenin and BMP Signaling Pathways. [PDF]

Anim Genet
Guo Y, Wang N, Hou X, Sun L, He H, Wang X.   +5 more
europepmc   +1 more source

Efficacy of Human Amniotic Membrane Stem Cell-Conditioned Medium on Improving In Vitro Maturation Efficiency of Mouse Oocytes. [PDF]

Cells
Ra K, Kim EY, Kang SK, Kim GA, Ra JC.
europepmc   +1 more source

Mechanisms of Rhubarb-Peach Kernel in treating gastric cancer: A network pharmacology and molecular docking study. [PDF]

Medicine (Baltimore)
Chen J, Xie M, Zhou X, Zhang X.
europepmc   +1 more source

Diversified cell origin of Helicobacter pylori eradication-responsive gastric diffuse large B-cell lymphomas. [PDF]

J Pathol
Kuo SH, Yeh KH, Lin CW, Chen LT, Liou JM, Shun CT, Lee HW, Wei MF, Wang HP, Wu MS, Cheng AL.   +10 more
europepmc   +1 more source

BCL2: A promising cancer therapeutic target

Biochimica Et Biophysica Acta: Reviews on Cancer, 2017
A remarkable characteristic of majority of cancer cells is that, they fail to undergo apoptosis, which in turn confers them a survival advantage over normal cells. Targeted cancer therapy aims at disrupting the functions of proteins that play an important role during cancer progression.
Sathees Chukkurumbal Raghavan
exaly   +5 more sources

Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction

Biochemical Pharmacology, 2017
Apoptosis is a highly regulated pathway of programmed cell death relying on the fine balance between pro and antiapoptotic binding partners. Overexpression of the antiapoptotic protein BCL2 in several cancers makes it an ideal target for chemotherapy, with minimum side effects.
Supriya V, Vartak, Divyaanka, Iyer, T R, Santhoshkumar, Sheetal, Sharma, Archita, Mishra, Gunaseelan, Goldsmith, Mrinal, Srivastava, Shikha, Srivastava, Subhas S, Karki, Avadhesha, Surolia, Bibha, Choudhary, Sathees C, Raghavan   +11 more
openaire   +3 more sources