Results 261 to 270 of about 150,149 (335)

Expression and Functional Analysis of the BCL2-Associated Agonist of Cell Death (BAD) Gene in the Sheep Ovary During the Reproductive Cycle

, 2018
Xiaohan Cao, Xiangyu Wang, Lulu Lu, Xiaoyu Li, Ran Di, Xiaoyun He, Wenping Hu, Xianyin Zeng, Qiuyue Liu, Mingxing Chu   +9 more
openalex   +1 more source

Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

Experimental Physiology, EarlyView.
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa, Sogand Gravina, Viktoria F. Richter, Dayana Mahizir, Kristina Anevska, Yeukai T. M. Mangwiro, James S. M. Cuffe, Fadi Charchar, Glenn D. Wadley, Deanne H. Hryciw, Karen M. Moritz, Mary E. Wlodek   +11 more
wiley   +1 more source

Enhancing the anti-cancer potential of resveratrol through cocrystal technology in colorectal cancerous rats. [PDF]

Sci Rep
Polati D, Neerati P.
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

The Interaction of Structural Analogues of Phenothiazines in p53-Dependent Cellular Signaling Pathways. [PDF]

ACS Omega
Giercuszkiewicz-Haśnik K, Pawicka P, Jeleń M, Morak-Młodawska B, Skonieczna M.   +4 more
europepmc   +1 more source

CD34⁺ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax

, 2019
Katharina Mattes, Mylène Gerritsen, Hendrik Folkerts, Marjan Geugien, Fiona A. van den Heuvel, Arthur Flohr Svendsen, Guoqiang Yi, Joost H.A. Martens, Edo Vellenga   +8 more
openalex   +2 more sources

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Antiapoptotic BCL2 family proteins BCL-XL and MCL1 as factors predicting resistance against venetoclax plus azacitidine for patients with newly diagnosed acute myelogenous leukemia. [PDF]

PLoS One
Kamihara Y, Kikuchi S, Ishikawa N, Shinomiya N, Kunimoto K, Horaguchi R, Fujihira T, Nabe Y, Minemura T, Ono K, Wada A, Dang NH, Sato T.   +12 more
europepmc   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

International Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Carlo Fremd, Laura Michel, Christian Maurer, Lars Buschhorn, Nicola Dikow, Fangyoumin Feng, Stefan Fröhling, Christel Herold‐Mende, Steffen Hirsch, Chen Hong, Daniel Hübschmann, Lena Jassowicz, Polina Kozyulina, Katrin Pfütze, Richard F. Schlenk, Hans‐Peter Sinn, Katharina Smetanay, Christoph Springfeld, Albrecht Stenzinger, Celina Wagner, Stephan Wolf, Andreas Trumpp, Dirk Jäger, Oliver Zivanovic, Marc Zapatka, Andreas Schneeweiss, Peter Lichter   +31 more
wiley   +1 more source

Hesperetin alleviates sepsis-associated acute respiratory distress syndrome via the PI3K/Akt/PTEN axis. [PDF]

Sci Rep
Ruan H, Yang D, Wang N, Liu J, Huang L.
europepmc   +1 more source