Results 271 to 280 of about 150,149 (335)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Mitochondria-derived peptides in liver disease: Emerging regulators of hepatic metabolism and therapeutic targets. [PDF]

Hepatol Commun
Thoudam T, Zeng G, Gao H, Jiang Y, Huda N, Yang Z, Ma J, Liangpunsakul S.   +7 more
europepmc   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Treg Susceptibility to Cladribine-Induced Depletion Correlates With Therapy Response in Patients With Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Cammarata I, Sartori G, Giacomelli T, Pinna V, Pinzon Grimaldos A, De Rosa G, Matarese G, Procaccini C, Mishra D, Di Mitri D, Gasperini C, Guerrera G, Sambucci M, Battistini L, Piconese S.   +14 more
europepmc   +1 more source

Interpreting pathways to discover cancer driver genes with Moonlight [PDF]

, 2020
al., et, Bailey, Matthew H., Colaprico, Antonio   +2 more
core   +1 more source

Effects of Silencing BAK1 and BCL2 Gene Expression on Proliferation, Invasion and Metastasis of HCC HepG2 Cells

, 2020
Ming Ma
openalex   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, Volume 158, Issue 4, Page 821-834, 15 February 2026.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

A Targeted Deletion of a Region Upstream from the Jκ Cluster Impairs κ Chain Rearrangement In Cis in Mice and in the 103/bcl2 Cell Line

, 1999
Laurentiu Cocea, Annie De Smet, Mahasti Saghatchian, Simon Fillatreau, Laurent Ferradini, Stéphane Schurmans, Jean–Claude Weill, Claude–Agnès Reynaud   +7 more
openalex   +2 more sources

Clinicopathological characteristics, genetic aberrations, and optimized treatment strategies in double-hit and triple-hit lymphoma: a multi-center cohort study. [PDF]

Mol Biomed
Shen YG, Ji MM, Shi Q, Wei XL, Fan L, Liu TB, Liu Y, Dong LH, Liang AB, Huang L, Zhou H, Huang HH, Yang SM, Wang XB, Tian YY, Zhu ZM, Bai O, Li F, Shi WY, Xu B, Wang X, Shi KQ, Tang W, Yi HM, Chen SY, Zheng Z, Cheng S, Xu PP, Zhao WL, Wang L.   +29 more
europepmc   +1 more source